Abstract
Recent theoretical studies of [m + n], m = 2, 3, and 4, cycloaddition reactions involving acetylene derivatives, n = 2, have been recompiled in this review. They include Diels–Alder and [3 + 2] cycloaddition reactions. The role of polar solvents and Lewis acid catalysts in these [m + 2] cycloaddition reactions are analysed. The studies carefully selected for this review attempt to provide an overview of the main approaches used to study the reactivity of C − C triple bonds as the n = 2 component in cycloaddition reactions, and a special focus has been given to the studies carried out within the Molecular Electron Density Theory as it provides insight into molecular mechanisms and reactivity in organic chemistry.
Author contributions
Bahyoune: writing – original draft, writing – review. Domingo: methodology, data curation, writing–review and editing, supervision. Bouissane: conceptualisation, formal analysis, methodology, writing–review and editing, supervision.
Acknowledgements
The authors are thankful to the Sultan Moulay Slimane University, Morocco for the partial support.
Disclosure statement
No potential conflict of interest was reported by the author(s).