Phytochemical Screening of Essential Oils and Ethanolic Extracts of Elsholtzia griffithii Fruits for Cosmeceutical Bioactivity

ABSTRACT

The purpose of this study was to examine the chemical composition of essential oil and crude ethanolic extract from the fruits of Elsholtzia griffithii, and to evaluate their cosmeceutical bioactivities such as anti-acne, antioxidant, and anti-tyrosinase effects using in vitro experimental models. The main components of essential oils were neral (48.72%) and geranial (37.34%). Kaempferol, a dietary flavonoid, was found (0.45%) in crude ethanolic extract. The essential oil inhibited Propionibacterium acnes strongly, whereas the crude ethanolic extract demonstrated modest antibacterial action. The essential oil and crude ethanolic extract demonstrated antioxidant and anti-tyrosinase effects.

KEYWORDS:

• Anti-acne
• antioxidant
• anti-tyrosinase
• Lamiaceae
• Elsholtzia griffithii

Acknowledgments

The authors would like to acknowledge the Rangsit University Research Institute in Thailand for providing financial support to this investigation (Grant No. 39/2564).

Disclosure statement

No potential conflict of interest was reported by the authors.

Authors’ Contributions Statement

OT and PS developed and optimized the plan for this investigation. TJ was responsible for the plant sampling, authentication, and pharmacognostic analyses. OT and WM engaged in biological activities with an emphasis on experiments that were investigated. PS and OT contributed to the chemical analysis, including HPLC and GC-MS, of the plant under investigation. Together, they summarized and discussed exhaustively all of the results and drafted the manuscript. All authors read and authorized the final manuscript. As the guarantor, PS is accountable for this research paper.

Additional information

Funding

The work was supported by the Rangsit University Research Institute [39/2564].