ABSTRACT
This study examined the effects of resistance training (RT), Tai Chi (TC) and combination intervention (RT & TC) on the oxidative stress, blood glucose and lipid metabolism and quality of life of elderly patients with type 2 diabetes mellitus (T2DM). Ninety-four elderly patients with T2DM were randomly divided into an RT group (RTG, n = 23), TC group (TCG, n = 24), combination intervention group (CIG, n = 24) and control group (CG, n = 23). All participants were given nutrition and medication. On this basis, RTG, TCG and CIG were administered for 24 weeks (3 times/week, 40 minutes/time). Observation indicators were malondialdehyde (MDA), superoxide dismutase (SOD), 8-hydroxy-2 deoxyguanosine (8-OHdG), fasting plasma glucose (FPG), postprandial plasma glucose (PPG), haemoglobin A1c (HbA1c) and diabetes specific quality of life (DSQL). RT, TC and joint intervention can reduce the oxidative stress damage on elderly patients with T2DM to different degrees, control the levels of blood sugar and blood lipid and improve the quality of life. Compared with single intervention, combination intervention can further reduce the level of oxidative stress but has no additional benefits on blood glucose and lipid control and quality of life.
Acknowledgements
This study was supported by Sichuan Sports College (Effects of combined resistance training and Tai Chi in elderly patients with type 2 diabetes mellitus. NO: SCSC-2021). It was supported by Sichuan Provincial Natural Science Foundation (24NSFSC1439).
Disclosure statement
No potential conflict of interest was reported by the author(s).
Author contributions
SWC and HL: designing this study, writing initial draft and revision, revising language and content, supervision, project administration, and funding acquisition. SWC: making figure and table. SWC and HL: rechecking the manuscript and putting forward suggestions for amendment. All authors contributed to the article and approved the submitted version.
Ethical considerations
This study was approved by the Ethics Committee of Sichuan Sports College (No. 2021.051) in accordance with the Helsinki Declaration, and informed consent was signed by the participants.
Submission statement
The data reported in this manuscript have not been published elsewhere and the manuscript is not under consideration for publication in another journal.