Xenobiotica, Volume 54, Issue 3 (2024)

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Xenobiotica, Volume 54, Issue 3 (2024)

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General Xenobiochemistry

Article
Prediction of combination effect of quinidine on the pharmacokinetics of tipepidine using a physiologically based pharmacokinetic model
Shun Hayashi, Hiroko Kawaguchi, Takao Watanabe, Izuru Miyawaki, Tatsuki Fukami & Miki Nakajima
Pages: 107-115
Published online: 17 Jan 2024
AbstractforPrediction of combination effect of quinidine on the pharmacokinetics of tipepidine using a physiologically based pharmacokinetic model | Full Text | References | PDF (1 MB) | EPUB | Supplemental
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Article
Development of a physiologically based pharmacokinetic model for levetiracetam in patients with renal impairment to guide dose adjustment based on steady-state peak/trough concentrations
Rongrong Wang, Tianlin Wang, Xueliang Han, Mengli Chen & Shu Li
Pages: 116-123
Published online: 21 Feb 2024
AbstractforDevelopment of a physiologically based pharmacokinetic model for levetiracetam in patients with renal impairment to guide dose adjustment based on steady-state peak/trough concentrations | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
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Animal Pharmacokinetics and Metabolism

Article
The metabolism of the orexin-1 selective receptor antagonist nivasorexant
Alexander Treiber, Swen Seeland, Belal Haschimi, Aude Weigel, Jodi T. Williams & Jerome Gabillet
Pages: 124-137
Published online: 01 Mar 2024
AbstractforThe metabolism of the orexin-1 selective receptor antagonist nivasorexant | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
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Article
Preclinical pharmacokinetic investigation of the bioavailability and skin distribution of HY-072808 ointment, a novel drug candidate for the treatment of atopic dermatitis, in minipigs by a newly LC-MS/MS method
Li Shao, Jiajia Mo, Qinlong Xu, Guangwei He, Chunyu Xing & Zhaoxing Chu
Pages: 138-149
Published online: 02 Apr 2024
AbstractforPreclinical pharmacokinetic investigation of the bioavailability and skin distribution of HY-072808 ointment, a novel drug candidate for the treatment of atopic dermatitis, in minipigs by a newly LC-MS/MS method | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
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Molecular Toxicology

Article
Sodium dodecylbenzene sulphonate (SDBS) present in detergents: action on the gills, skin, and blood of D. rerio fish
Eduardo Libanio Reis Santos, Odaiza Silva, Jeffesson de Oliveira-Lima & Maria Izabel Camargo-Mathias
Pages: 150-159
Published online: 16 Feb 2024
AbstractforSodium dodecylbenzene sulphonate (SDBS) present in detergents: action on the gills, skin, and blood of D. rerio fish | Full Text | References | PDF (9.4 MB) | EPUB
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Pharmacogenetics

Article
Effects of pharmacogenetics on pharmacokinetics and toxicity of doxorubicin in Egyptian breast cancer patients
N. F. Ebaid, K. S. Abdelkawy, M. A. Shehata, H. F. Salem, G. Magdy, R. R. S. Hussein & F. Elbarbry
Pages: 160-170
Published online: 02 Apr 2024
AbstractforEffects of pharmacogenetics on pharmacokinetics and toxicity of doxorubicin in Egyptian breast cancer patients | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
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