Semi-automatic artifact quantification in thermal ablation probe and algorithms for the evaluation of metal artifact reduction

Abstract

Objectives

To compare metal artifacts and evaluation of metal artifact reduction algorithms during probe positioning in computed tomography (CT)-guided microwave ablation (MWA), cryoablation (CRYO), and radiofrequency ablation (RFA).

Materials and methods

Using CT guidance, individual MWA, CRYO, and RFA ablation probes were placed into the livers of 15 pigs. CT imaging was then performed to determine the probe’s position within the test subject’s liver. Filtered back projection (B30f) and iterative reconstructions (I30-1) were both used with and without dedicated iterative metal artifact reduction (iMAR) to generate images from the initial data sets. Semi-automatic segmentation-based quantitative evaluation was conducted to estimate artifact percentage within the liver, while qualitative evaluation of metal artifact extent and overall image quality was performed by two observers using a 5-point Likert scale: 1-none, 2-mild, 3-moderate, 4-severe, 5-non-diagnostic.

Results

Among MWA, RFA, and CRYO, compared with non-iMAR in B30f reconstruction, the largest extent of artifact volume percentages were observed for CRYO (11.5–17.9%), followed by MWA (4.7–6.6%) and lastly in RFA (5.5–6.2%). iMAR significantly reduces metal artifacts for CRYO and MWA quantitatively (p = 0.0020; p = 0.0036, respectively) and qualitatively (p = 0.0001, p = 0.0005), but not for RFA. No significant reduction in metal artifact percentage was seen after applying iterative reconstructions (p > 0.05). Noise, contrast-to-noise-ratio, or overall image quality did not differ between probe types, irrespective of the application of iterative reconstruction and iMAR.

Conclusion

A dedicated metal artifact algorithm may decrease metal artifacts and improves image quality significantly for MWA and CRYO probes. Their application alongside with dedicated metal artifact algorithm should be considered during CT-guided positioning.

Keywords:

• Metal artifact reduction
• computed tomography
• image quality
• microwave ablation
• radiofrequency ablation
• cryoablation
• CT-guidance

Ethical approval

The study was performed according to rules outlined by the local and governmental animal care committee instituted by the German government. The ethics committee approved this study as a part of other trials.

Author contributions

The corresponding author declares that all authors have read the manuscript and have given permission to submit the work in its current version. All authors have made substantial contributions to conception and design of the study, acquisition data, or analysis and interpretation of data; drafting the article or revising it.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

PD Dr. Thuy Duong Do was supported by a grant from the Medical Faculty of the University of Heidelberg.