The differences in the count of B lymphocytes in atopic dermatitis patients with and without dupilumab therapy and in healthy subjects in pollen season and out of pollen season

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Authors contribution

All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship for this article, take responsibility for the integrity of the work as a whole, and have given their approval for this version to be published.

Ethical approval

This study was approved by Ethics committee of the Faculty Hospital Hradec Králové, Charles University of Prague, Czech Republic. Reference number is: 2021 10 P 03. The study was conducted according to the guidelines of the Declaration of Helsinki, and approved by the Institutional Review Board - Ethics committee of the Faculty Hospital Hradec Králové, Charles University of Prague, Czech Republic. Data of Approval 4 September 2021.The study was conducted in accordance with the Helsinki Declaration of 1964 and all subsequent amendments, and all patients provided written informed consent. Patient-level data used for this analysis were de-identified.

Medical writing/editorial assistance

The article was written by the main author, no other services and Editorial assistence were needed.

Prior publication

This manuscript is not based on work that has been previously presented/published.

Informed Consent

Informed consent was obtained from all subjects involved in the study.

Disclosures statement

No potential conflict of interest was reported by the author(s). Jarmila Čelakovská, Eva Čermákova, Petra Boudková, Ctirad Andrýs, Jan Krejsek has nothing to disclose.

Data availability [database]

The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.

Additional information

Funding

Charles University, Medical Faculty Hradec Králové, Cooperatio, INDI 207034 (the financial support was intended for research purposes to examine the immunological profile). Supported by MH CZ - DRO (UHHK, 00179906). The Service Fee was funded by the authors. This work supported by Univerzita Karlova v Praze.