Efficacy and safety of a novel 785 nm picosecond neodymium-doped yttrium aluminum garnet laser for the treatment of facial benign pigmented lesions in Asian skin: a pilot study

Abstract

Background and Objectives

Benign pigmented lesions and a general uneven tone in people with skin of color are growing issues that have been presented to dermatologists. To the best of our knowledge, this is the first controlled study to examine the efficacy and safety of using the newly introduced 785 nm neodymium-doped yttrium aluminum garnet (Nd:YAG) picosecond laser to treat facial benign pigmented lesions in Asian patients with diffractive lens array.

Materials and Methods

A 785 nm Nd:YAG picosecond laser was used to treat 15 healthy female volunteers older than 18 years who had Fitzpatrick skin types II–IV and facial benign pigmented lesions. Each volunteer received five weekly treatments in dual modes. The clinical improvement was assessed by independent investigators and by objectively measuring the melanin index.

Results

After the treatment, the melanin and erythema indices decreased, and the pigmented lesions showed clinical improvements. No serious adverse effects were observed during the study period.

Conclusions

A 785 nm Nd:YAG picosecond laser may be safe and effective in treating facial benign pigmented lesions in Asian skin.

Keywords:

• Picosecond
• laser
• dyschromia
• pigmentation

Disclosure statement

Dr. Kui Young Park works as a consultant and speaker for Laseroptek Inc. The remaining authors have no conflicts of interest to declare.

Data availability statement

The data that support the findings of this study are available from the corresponding author, PKY, upon reasonable request.

Additional information

Funding

This work was funded by Laseroptek Inc. This research was supported by the Chung-Ang University Research Grants in 2022.