Association between ABO blood groups and preeclampsia

ABSTRACT

Objective

To determine the association between the ABO blood group and preeclampsia.

Methods

This is a case-control study that included patients with (n = 253) and without (n = 457) preeclampsia/eclampsia in Northeastern Mexico. Data were obtained from electronic medical records. Binary multiple logistic regression analysis was used for analyzing the association between the ABO blood group and preeclampsia according to parity status while adjusting for potential confounders.

Results

Blood groups A, B, and AB showed adjusted odds ratios of 0.6 (95%CI 0.3-1.0), 1.1 (95%CI 0.6-2.2), and 0.3 (95%CI 0.1-1.1) in multiparous women, respectively. No association was found in nulliparous women either.

Conclusions

ABO blood groups were not associated with preeclampsia in Mexican women.

KEYWORDS:

• Preeclampsia
• ABO blood-group system
• risk factors
• association

Acknowledgments

We would like to thank the personnel of the Clinical File Department of the General Hospital of Zone No. 6 of the Mexican Institute of Social Security.

Disclosure statement

No potential conflict of interest was reported by the authors.

Supplementary material

Supplemental data for this article can be accessed online at https://doi.org/10.1080/10641955.2023.2209640

Author contributions

HFCF and AMSM participated in research conception and design, data analysis and interpretation, manuscript writing, and critical revision. LAGH, SDGR, JDTB, and FJGG participated in data acquisition and interpretation and critical revision of the manuscript. All authors have seen and approved the final version.

Additional information

Funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.