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ABSTRACT
In this study, hydrothermal-calcination method was employed to synthesize pure vanadium oxide and zinc doped vanadium oxide powders. The crystal structure, morphology, chemical state and light absorption properties of the powders were also thoroughly analyzed. The antimicrobial effect against Candida albicans was evaluated by the circle of inhibition method and plate colony counting method. This study reveals the antibacterial mechanism of oxygen defects generating reactive oxygen species, leading to oxidative stress damage. This study not only demonstrates the potential of vanadium oxides as an efficient antimicrobial agent, but also provides a strong experimental basis and theoretical support for the design and optimization of novel antimicrobial materials by modulating the defect engineering of the materials. This finding provides a new perspective for the development of antimicrobial strategies against microorganisms and has important application prospects for the clinical treatment of Candida albicans infections.
Disclosure statement
No potential conflict of interest was reported by the author(s).