Chemistry and Bioactivity of Physciaceae Lichens Pyxine consocians. and Heterodermia leucomelos.

Abstract

Cabraleadiol monoacetate, atranorin, methyl-β.-orcinolcarboxylate, zeorin, 4-O.-methylcryptochlorophaeic acid, and lichexanthone were isolated from the lichen Pyxine consocians Vainio... Heterodermia leucomelos (L)... Poelt contained a new triterpenoid, 6α-hydroxyhop-21β.H-22(29)-en, along with atranorin, zeorin, glyceryl trilinolate, and 3,6-dimethyl-2-hydroxy-4-methoxybenzoic acid. Cabraleadiol monoacetate, 4-O.-methylcryptochlorophaeic acid, lichexanthone, and 3,6-dimethyl-2-hydroxy-4-methoxybenzoic acid showed mosquito larvicidal activity against the second instar larvae of Aedes aegypti.. Lichexanthone exhibited human sperm motility enhancing activity.

Keywords:

• Bioactivity
• Heterodermia leucomelos
• lichen
• lichen metabolites
• new triterpenoid
• Physciaceae
• Pyxine consocians