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Mini-Review

Sulfenamide formation – chemical and biochemical reactions and their applications in cell biology

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Pages 293-312 | Received 12 Jul 2023, Accepted 24 Oct 2023, Published online: 01 Nov 2023
 

Abstract

Sulfenamides are organosulfur compounds that contain a single bond between nitrogen and sulfur in their structures. Sulfur can react with nucleophiles to yield new compounds. The compounds having nitrogen–sulfur bonds are used in polymers for a variety of purposes, including medicines, agrochemicals, veterinary medications, and environmental studies. This review will examine several chemical reactions that lead to sulfenamide production as well as how they are used in cell biology and biochemical applications.

GRAPHICAL ABSTRACT

Acknowledgements

The authors thank Richa Verma and Dr. Ming Fu for their critical reviews of this article. All the authors have contributed to the conceptualization, writing, and revision of this article. This work has been supported by a Discovery Grant from Natural Sciences and Engineering Research Council of Canada to Rui Wang [RGPIN-2023-05099].

Disclosure statement

No potential conflict of interest was reported by the author(s).

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