An Orthokeratinized Odontogenic Cyst in an 8-Year-Old: A Case Report with Differential Diagnosis

ABSTRACT

Background

Orthokeratinized odontogenic cyst (OOC) is a rare developmental odontogenic cyst that is clinically and histomorphologically different than odontogenic keratocyst (OKC).

Case Description

OOC is a distinct entity from OKC with a unique biological behavior, pathogenesis, and prognosis. The distinction between these entities is paramount because unlike OKCs, OOCs rarely recur after simple enucleation and are not associated with nevoid basal cell carcinoma syndrome. We present a case of an 8-year-old male with an OOC of the right posterior mandible along with a differential diagnosis and discussion of OOCs and its common mimics.

KEYWORDS:

• Clinicopathologic conference
• differential diagnosis
• mandibular cyst
• odontogenic cyst
• orthokeratinized odontogenic cyst
• unilocular lesion
• pediatric jaw cyst

Disclosure Statement

No potential conflict of interest was reported by the authors.

Additional information

Notes on contributors

Chan M. Park

Chan M. Park, DDS, MD is a staff oral and maxillofacial surgeon in the Department of Maxillofacial Surgery at Kaiser Permanente in Anaheim, California. He is a fellow in the American College of Surgeons and American College of Dentists. Conflict of Interest Disclosure: None reported.

Jeffrey A. Elo

Jeffrey A. Elo, DDS, MS is the Drs. Daljit & Elaine Sarkaria Professor of Advanced Oral Diagnosis & Therapeutics and a professor of oral and maxillofacial surgery at the Western University of Health Sciences College of Dental Medicine in Pomona, California; and is a clinical assistant professor in the department of oral and maxillofacial surgery at the Loma Linda University School of Dentistry in Loma Linda, California. He is a fellow in the American College of Surgeons, American College of Dentists, and International College of Dentists. Conflict of Interest Disclosure: None reported.

Mark Mintline

Mark Mintline, DDS is an associate professor of oral and maxillofacial pathology at the Western University of Health Sciences College of Dental Medicine in Pomona, California; and is the laboratory director of the WesternU Health Oral Pathology Laboratory.

Elizabeth Orbeta

Elizabeth Orbeta, MS is a dental student at the Western University of Health Sciences College of Dental Medicine in Pomona, California.

Stephen Seongeun Koh

Stephen Seongeun Koh, MD is a clinical pathologist at Kaiser Permanente in Anaheim, California. Conflict of Interest Disclosure: None reported.