ABSTRACT
DNA sequencing is not enough to grasp the complexity of genome organization and function. The four-dimensional (three in space, one in time) configuration of the eukaryotic nucleus varies with cell types, during development and in diseased tissues, and has to be taken into account to decipher genome function. To study, discuss, and advance in such direction, the International Nucleome Consortium COST Action, funded by the European Union, held its concluding symposium ‘The Genome in Space and Time’ at the Ionian University in Corfu, Greece, on September 10–13, 2023.
Acknowledgments
We would like to thank the organizers of this COST meeting in Corfu, Franck Fackelmayer, Spyridon Doukakis, Panayiotis Valmos and Marios Krokidis and the Ionian University. Our thanks go as well to COST Action International Nucleome Consortium (INC) CA18127 and its organizing committee. Finally, we thank all the participants of the Genome in Space and Time meeting (https://inc-cost.eu/corfu-2023) for sharing their latest results and their scientific generosity, including those we were not able to mention in this synthetic report.
Disclosure statement
No potential conflict of interest was reported by the author(s).
Data availability statement
Data sharing is not applicable to this article as no new data were created or analyzed in this study.
Author contribution statement
M.R.-M. and KB drafted, conceptualized and wrote the manuscript. K.B. revised the manuscript. M.R.-M. design the figure. All authors have read and approved its submission and agreed to be accountable for all aspect of the work.