Predictors for low coverage of uptake of second dose of measles vaccine among children in sub-Saharan Africa, 2023: a systematic review and meta-analysis

ABSTRACT

Background

Measles became a public health important disease in sub-Saharan Africa. World Health Organization recommended measles-containing vaccine dose 2 (MCV2) through routine service delivery. This study aims to determine coverage of second-dose measles vaccination uptake and its predictors among children aged 24–35 months in sub-Saharan Africa.

Methods and materials

We conducted an extensive search of literature as indicated in the guideline of reporting systematic review and meta-analysis (PRISMA). The databases used were PubMed, Google Scholar, and HINARI literature.

Results

The overall uptake of the second dose of measles vaccine uptake was 41% (95% CI: 28.90–53.47). Caregiver's awareness of the importance of the second dose of measles (2.51, 95% CI 1.77, 3.25), educational status of mothers (1.30, 95% CI 1.16, 1.45), distance from vaccination site (1.22, 95% CI 1.12, 1.32), and attending four and above ANC visit (2.72, 95% CI 2.29, 3.15) were determinants for second dose measles vaccine uptake.

Conclusion

Coverage of the second dose of measles uptake in Sub-Saharan Africa was low (41%) which is lower than the recommendation from WHO. Therefore policymakers and stakeholders should increase mother's awareness. Also, special strategies should be developed for those who are far from the vaccination site.

Abbreviation and acronyms

ANC: Ante Natal Care; JBI: Joanna Briggs Institute; MCV1: Measles containing vaccine dose 1; MCV2: Measles containing vaccine dose 2; WHO: World Health Organization

KEYWORDS:

• Second dose measles vaccine
• utilisation of measles vaccine
• vaccine uptake

Acknowledgment

Authors of the primary research used on this systematic meta-analysis never need to be missed from acknowledgment.

Additional file (s1–s3)

• S1. Prisma checklist for the study of the uptake of the second dose of measles vaccine

• S2. Newcastle – Ottawa Quality Assessment Scale for Cohort Studies

• S3. Quality assessment score for individual items for the study of uptake of the second dose of measles vaccine

Authors’ contributions

TM AM and YF built the search strategy, and make the first draft. All authors (TM AM, YF, KH, AH, and GJ participated in data curation, methodology, analysis and writing and editing of the final draft. part. All authors read and approved the final manuscript.

Availability of data and materials

The data is available with no restriction. It could be obtained from corresponding author (Tamirat Melis, Email address: [email protected]

Ethics approval and consent to participate

Not applicable

Consent for publication

Not applicable

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

Not applicable.

Notes on contributors

Tamirat Melis

Tamirat Melis is currently working as lecturer at Department of Public Health, College of Medicine and Health Science, Wolkite University, Wolkite, Ethiopia.

Ayenew Mose

Ayenew Mose is lecturer of wolkite university, Department of Midwifery, College of Medicine and Health Science, Wolkite University, Wolkite, Ethiopia, But currently he is attending PhD program in the Ritchie Centre, Hudson Institute of Medical Research, Clayton, Australia.

Yohannes Fikadu

Yohannes Fikadu is currently working as lecturer of Wolkite University, Department of Midwifery, College of Medicine and Health Science, Wolkite University, Wolkite, Ethiopia.

Kassahun Haile

Kassahun Haile is currently lecturer of Wolkite University Department of medical laboratory, College of Medicine and Health Science, Wolkite University, Wolkite, Ethiopia.

Aklilu Habte

Aklilu Habte Is working as lecturer of Department of Public Health, College of Medicine and Health Science, Wachemo University, Hosanna, Ethiopia.

Gemechu Jofiro

Gemechu Jofiro Department of Nurse, College of Medicine and Health Science, Arsi University, Asela, Ethiopia.