Role of cell membrane homeostasis in the pathogenicity of pathogenic filamentous fungi

ABSTRACT

The cell membrane forms a fundamental part of all living cells and participates in a variety of physiological processes, such as material exchange, stress response, cell recognition, signal transduction, cellular immunity, apoptosis, and pathogenicity. Here, we review the mechanisms and functions of the membrane structure (lipid components of the membrane and the biosynthesis of unsaturated fatty acids), membrane proteins (transmembrane proteins and proteins contributing to membrane curvature), transcriptional regulation, and cell wall components that influence the virulence and pathogenicity of filamentous fungi.

KEYWORDS:

• Cytoplasmic membrane homeostasis
• pathogenicity
• filamentous fungi
• membrane lipid metabolism
• membrane curvature
• growth and development

Acknowledgements

This work was financially supported by the Natural Science Foundation of Yunnan Province (202301AT070487), Scientific Research Fund Project of Education Department of Yunnan Province (2023Y0902), the Major Science and Technology Project of Yunnan and Kunming (202202AE090036), the Science and Technology Project of Yunnan provincial tobacco company (NO.2022530000241019), and Yunnan provincial Municipal Education Commission Innovation Team Project (2022[69]) grants.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Data availability statement

Data availability is not applicable to this article as no new data were created or analysed in this study.

Correction Statement

This article has been republished with minor changes. These changes do not impact the academic content of the article.

Additional information

Funding

The work was supported by the Natural Science Foundation of Yunnan Province [202301AT070487]; Yunnan provincial Municipal Education Commission Innovation Team Project (2022[69]); Science and Technology Project of Yunnan provincial tobacco company [NO.2022530000241019]; Scientific Research Foundation of Education Department of Anhui Province of China [2023Y0902].