Change in intention and hesitancy regarding COVID-19 vaccines in a cohort of adults in Quebec during the pandemic

ABSTRACT

Although COVID-19 vaccine uptake was high in Quebec for the primary series, vaccine acceptance decreased for the subsequent booster doses. This article presents the evolution of vaccine intention, self-reported vaccination behaviors, and vaccine hesitancy over 2 years. A series of cross-sectional surveys were conducted in Quebec between March 2020 and March 2023, with a representative sample of 3,330 adults recruited biweekly via a Web panel. Panelists could have answered multiple times over the course of the project. A cohort of respondents was created to assess how attitudes and behaviors about COVID-19 vaccines evolved. Descriptive statistics and multivariate logistic regressions were performed. Among the 1,914 individuals with no or low intention of getting vaccinated in Fall 2021 (Period 1), 1,476 (77%) reported having received at least two doses in the Winter 2023 (Period 2). Not believing in conspiracy theory (OR = 2.08, 95% CI: 1.65–2.64), being worried about catching COVID-19 (OR = 2.12, 95% CI: 1.65–2.73) and not living in a rural area (ORs of other areas are 2.27, 95% CI: 1.58–3.28; 1.66, 95% CI: 1.23–2.26; 1.82 95% CI: 1.23–2.73) were the three main factors associated with being vaccinated at Period 2. Among the 11,117 individuals not hesitant at Period 1, 1,335 (12%) became hesitant at Period 2. The three main factors significantly associated with becoming vaccine hesitant were the adherence to conspiracy theories (OR = 2.28, 95% CI: 1.95–2.66), being a female (OR = 1.67, 95% CI: 1.48–1.90) and being younger than 65 years old (the ORs for 18–34, 35–49, and 50–64 compared with 65 and over are 2.82, 95% CI: 2.32–3.44; 2.39, 95% CI: 2.00–2.86 and 1.82, 95% CI: 1.55–2.15 respectively). As the pandemic is over, monitoring the evolution of vaccine attitudes and uptake will be important.

KEYWORDS:

• Vaccine hesitancy
• vaccine intention
• longitudinal study
• COVID-19
• immunization

Acknowledgments

Thanks to the Ministère de la santé et des services sociaux du Québec for funding this study and to the survey participants. We would also like to thank Mélanie Tessier for her contribution with the surveys and Mamady Magassouba for his contribution in the conception, design, an analysis of the cohort.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Author contributions

All the authors contributed to all aspects of the work.

Supplementary material

Supplemental data for this article can be accessed on the publisher’s website at https://doi.org/10.1080/21645515.2024.2309006

Additional information

Funding

This project was funded by the Ministère de la Santé et des services sociaux du Québec.