https://orcid.org/0009-0009-7214-5931
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ABSTRACT
Rubella is a major cause of congenital defects, and the presence of rubella infection in a pregnant woman may lead to fetal death or congenital defects known as congenital rubella syndrome(CRS). Since China has not yet established a national CRS surveillance system, the true incidence cannot be determined. To understand the disease burden and epidemiological characteristics of CRS cases in China, the article reports the first case of CRS in Quzhou, China, and conducts a retrospective analysis of related cases that have been reported in China over the past decade. Because the availability of rubella-containing vaccines (RCV) was not widespread in China before 2008, women of childbearing age born before 2008 are generally unvaccinated against RCV. Due to the lack of routine CRS monitoring and screening, CRS is underreported in China. Vaccination of nonimmune women of childbearing age with RCV and establishing a sensitive and timely case-based CRS surveillance system can accelerate the elimination of rubella and CRS.
Acknowledgments
The authors thank their families, Huashu Township Health Service Center, Quzhou People’s Hospital, and Quzhou Center for Disease Control and Prevention.
Author contributions disclaimer
Xiaoying Gong wrote the article and Zhiying Yin critically reviewed the article; Canjie Zheng, Quanjun Fang, and Wenjie Xu were involved in the epidemiological investigation and data analysis. All authors have agreed on the journal to which the article will be submitted and all agree to take responsibility for all aspects of the work.
Disclosure statement
No potential conflict of interest was reported by the author(s).
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The patient consented to the publication of this article.