The consequences of poor dietary patterns on the proliferation of non-alcoholic fatty liver disease

Abstract

Triglyceride (TG) buildup in the liver is a hallmark of the metabolic disorder of non-alcoholic fatty liver disease (NAFLD). The four pathogenic categories mainly followed by the NAFLD pathway are hepatocellular carcinoma, non-alcoholic steatosis, steatohepatitis, and progressive fibrosis or cirrhosis. The likelihood of developing NAFLD rises with obesity and insulin resistance. Aging, gender, culture, and ethnicity are all associated with NAFLD, which substantially correlates to liver disorders in both kids and adults. It is prevalent throughout all age ranges. Visceral obesity appears to be exacerbated by poor lifestyle choices such as hypercaloric diets, particularly those high in trans-fat or saturated fat and cholesterol, and sugar-sweetened beverages. Decreasing calorie intake, boosting soy protein and whey ingestion, supplementing with monounsaturated fats, omega-3 fatty acids, and fiber, and changing one’s lifestyle are the initial steps in managing this condition. Polyphenolic substances also have both therapeutic and preventative benefits. Activity and exercise that promotes weight loss and lessen liver fat formation are just as important as maintaining a balanced diet. The patients turn into susceptible to liver transplantation owing to improper concern (the end stage of NAFLD). Examining the impact of nutrition on nonalcoholic fatty liver disease (NAFLD) is the goal of this review. Included in this is a result of an unbalanced intake of macronutrients. The pathogenesis of NAFLD involves nutrition. Individuals with NAFLD must be recommended to restrict calorie consumption and set intake limits when following low-fat/carbohydrate diets.

Keywords:

• NAFLD
• hepatitis
• cirrhosis
• insulin resistance
• poor lifestyle
• Mediterranean diets

Reviewing Editor:

• M. Luisa Escudero-Gilete
• Universidad de Sevilla
• Spain

Subjects:

• Biochemistry
• Nutrition
• Pharmaceutical Science
• Pharmacology
• Epidemiology
• Immunology
• Allied Health
• Medicine

Disclosure statement

No potential conflict of interest was reported by the author(s).

Data availability statement

The data that support the findings of this study are available on request from the corresponding author.

Additional information

Funding

No funding was received to undergo the study.