An overview on the modulation of pesticide detoxification mechanism via salicylic acid in the plants

ABSTRACT

The continuous application of pesticides leads to several harmful effects on the ecosystem and get accumulated in the food chain. To regulate the toxicity of pesticides there are several strategies available. In relation to this, the endogenous as well as exogenous role of salicylic acid in pesticide regulation is less overviewed. To regulate the pesticide stress, in presence of salicylic acid, the genes, and proteins related to reduced glutathione (GSH) metabolism, biosynthesis of secondary metabolites, glyoxylate, and dicarboxylate metabolism get upregulated and are found to be more differentially expressed for pesticide detoxification. Salicylic acid regulates pesticide toxicity by activating gene expression of P450, antioxidant enzymes, ABC transporters subfamilies to form a defense network. In this context, the present review tries to comprehend the pesticide detoxification processes involving salicylic acid to regulate the stress caused thereby in plants and further utilize this strategy for wider application.

KEYWORDS:

• Pesticide
• growth
• agriculture crops
• phytohormones
• signaling molecules

Acknowledgments

The authors are grateful to the Head, Department of Botany, Institute of Science, Banaras Hindu University, Varanasi, for providing the necessary facilities. The Banaras Hindu University is also thankfully acknowledged for providing financial assistance to Dr. A. Singh as PI under the IoE seed grant scheme (Dev. IoE Scheme No. 6031). The authors P.K. Yadav and A. Kumar are also thankful to the UGC Non-Net Fellowship scheme (R/Dev./Sch./25437) and the CSIR–UGC, New Delhi (UGC-Ref. No.974/CSIR-UGC NET DEC.2017) repectively, for providing financial assistance.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Author contributions

The authors A Kumar and PK Yadav have equally contributed to writing the manuscript under the guidance of author A Singh. Another author, S Singh, has helped to finalize the manuscript’s figure and format.

Correction Statement

This article has been republished with minor changes. These changes do not impact the academic content of the article.

Additional information

Funding

The work was supported by the BHU Non-Net [25437]; IoE, B.H.U. [6031]; University Grant Commission, New Delhi [UGC-Ref.No. 974/CSIR-UGC NET DEC. 2017].