Abstract
Methods
Related studies on PD and ferroptosis were searched in Web of Science Core Collection (WOSCC) from inception to 2023. VOSviewer, CiteSpace, RStudio, and Scimago Graphica were employed as bibliometric analysis tools to generate network maps about the collaborations between authors, countries, and institutions and to visualize the co-occurrence and trends of co-cited references and keywords.
Results
A total of 160 original articles and reviews related to PD and ferroptosis were retrieved, produced by from 958 authors from 162 institutions. Devos David was the most prolific author, with 9 articles. China and the University of Melbourne had leading positions in publication volume with 84 and 12 publications, respectively. Current hot topics focus on excavating potential new targets for treating PD based on ferroptosis by gaining insight into specific molecular mechanisms, including iron metabolism disorders, lipid peroxidation, and imbalanced antioxidant regulation. Clinical studies aimed at treating PD by targeting ferroptosis remain in their preliminary stages.
Conclusion
A continued increase was shown in the literature within the related field over the past decade. The current study suggested active collaborations among authors, countries, and institutions. Research into the pathogenesis and treatment of PD based on ferroptosis has remained a prominent topic in the field in recent years, indicating that ferroptosis-targeted therapy is a potential approach to halting the progression of PD.
Data Sharing Statement
All data used or analyzed during the study were included in this article. Further inquiries about the data are available from the corresponding author on reasonable request.
Author Contributions
All authors made significant contributions to this study, both in terms of conceptualization, study design, data acquisition, analysis and interpretation; and were involved in drafting or revising the article, agreeing on the journal to which the article should be submitted, and ultimately approving the version to be published, and agreeing to take responsibility for all aspects of the work.
Disclosure
The authors report no conflicts of interest in this work.