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Case reports

Myocarditis Following Inactivated SARS-CoV-2 Vaccine (Vero Cell) in an Adult Female in Vietnam: A Case Report

, , , ORCID Icon, & ORCID Icon
Pages 551-559 | Received 10 May 2023, Accepted 03 Sep 2023, Published online: 15 Sep 2023
 

Abstract

During the Coronavirus disease 2019 (COVID-19) pandemic, vaccination against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has proven to be an important measure to help control disease spread and improve patient outcome. There are four distinct vaccine categories: inactivated viral vaccines, messenger RNA (mRNA) vaccines, adenovirus vector–based vaccines, and adjuvanted protein vaccines. In 2021, increased cases of myocarditis and pericarditis were reported after mRNA and adenovirus vector–based COVID-19 vaccination. A similar reporting pattern has not been observed after receipt of inactivated virus vaccines. Here, we present a case of clinically suspected acute myocarditis in a 26-year-old female, occurring 11 days after the administration of Sinopharm Vero Cell, an inactivated virus COVID-19 vaccine. This event led to acute heart failure, with marked clinical resolution observed within 34 days.

Informed Consent Statement

Written informed consent has been obtained from the patient to publish this paper, including publication of any accompanying images. Institutional approval was not required to publish the case details.

Acknowledgments

We would like to express our gratitude to the interventional cardiology department for providing a high standard of patient care and tremendous assistance with our work in the publishing of this paper.

Author Contributions

All authors made a significant contribution to the work reported, whether that is in the conception, study design, execution, acquisition of data, analysis and interpretation, or in all these areas; took part in drafting, revising or critically reviewing the article; gave final approval of the version to be published; have agreed on the journal to which the article has been submitted; and agree to be accountable for all aspects of the work.

Disclosure

Prof. Dr. Binh Quang Truong reports personal fees from Novartis and Servier, outside the submitted work. The authors declare no other conflicts of interest in this work.

Additional information

Funding

This study received no external funding.