Abstract
Background
Although percutaneous osteoplasty (POP) has been widely accepted and is now being performed for the treatment of painful bone metastases outside the spine. It is emerging as one of the most promising procedures for patients with painful bone metastasis who are unsuitable for surgery or who show resistance to radiotherapy and/or analgesic therapies. However, there are only scarce reports regarding osteoplasty in painful sternal metastases.
Subjects and Method
We report four patients with sternal metastases suffered with severe pain of anterior chest wall. The original tumors included lung cancer and thyroid cancer. For the initially pain medication failing, all the four patients received POP procedure under fluoroscopic and cone-beam CT (CBCT) guidance, and obtained satisfying resolution of painful symptoms at 6-month postop follow-up.
Conclusion
POP is a safe and effective treatment for pain caused by metastatic bone tumors in the sternum. In practice, however, percutaneous puncture of pathologic sternal fractures can be a challenge because of the long flat contour and the defacement by lytic tumor of bony landmarks. We find that the use of fluoroscopic and CBCT can facilitate POP for flat bone fractures with displacing the trajectory planning, needle advancement, and cement delivery in time.
Ethics, Consent and Permissions
Written informed consent has been provided by the four patients to use their clinical data and pictures for the report. Ethics approval is not required for a retrospective report of anonymous patient data. No institution approval was required to publish the case details.
Acknowledgments
This paper has been uploaded to [Research Square] as a preprint: [https://www.researchsquare.com/article/rs-576606/v1].
Author Contributions
All authors have made a significant contribution to the work reported, whether that is in the conception, study design, execution, acquisition of data, analysis and interpretation, or in all these areas. They have drafted or written, or substantially revised or critically reviewed the article, and agreed on the journal to which the article will be submitted.All authors have reviewed and agreed on all versions of the article before submission, during revision, the final version accepted for publication, and any significant changes introduced at the proofing stage. And all authors have agree to take responsibility and be accountable for the contents of the article.
Disclosure
The authors report no conflicts of interest in this work.