Agreement of Corneal Diameter and Anterior Chamber Depth Measurements with the IOLMaster 500 and the IOLMaster 700 Optical Biometers in Myopic Eyes

Abstract

Purpose

To assess the agreement in automated corneal diameter (CD) and anterior chamber depth (ACD, measured from corneal epithelium to lens) distances measurements between the IOLMaster 500 and 700 optical biometers in myopic eyes.

Methods

One hundred and sixteen eyes of 116 myopic patients aged between 21 to 60 years were included in this study. Measurements of CD and ACD distances were taken with each biometer for all patients in the same session. A t-test and a p-value less than 0.05 was considered statistically significant when the measurements were compared. The agreement between biometers was studied by applying a Bland–Altman analysis.

Results

The mean CD values obtained using the IOLMaster 500 and 700 biometers were 12.26±0.35 mm and 12.13±0.34 mm, respectively. The mean ACD distance values were 3.61±0.29 mm and 3.62±0.31, for the IOLMaster 500 and 700 biometers, respectively. There were statistically significant differences between the two devices only for CD measurements (p<0.001), but not for ACD measurements (p=0.26). The limits of agreement obtained were wide in both types of measurements, being 0.422 mm for the CD distance and 0.389 mm for the ACD distance.

Conclusion

There were statistically significant differences between the IOLMaster 500 and 700 biometers regarding CD but not in ACD measurements in healthy myopic eyes. These differences could be clinically significant in some cases. According to these results, medical judgement should be used to assess whether the two devices could be used interchangeably for CD and ACD measurements during the clinical practice.

Keywords:

• anterior chamber depth
• white-to-white
• IOLMaster 500
• IOLMaster 700
• optical biometry

Acknowledgments

The current research was supported by an investigator-sponsored study from STAAR Surgical AG.

Disclosure

Dr Pedro Tañá-Rivero reports grants from Staar Surgical, during the conduct of the study; grants from Alcon Labs, grants from AST Products Inc., Carl Zeiss Meditec, Heidelberg Engineering, Hoya, HumanOptics, Johnson&Johnson, and grants from BVI, outside the submitted work. The authors report no other conflicts of interest in this work.