Comfort After Refitting Symptomatic Habitual Reusable Toric Lens Wearers with a New Daily Disposable Contact Lens for Astigmatism

Abstract

Purpose

To subjectively evaluate comfort with a daily disposable (delefilcon A for astigmatism) contact lens compared to other common weekly/monthly soft toric contact lenses in symptomatic wearers.

Methods

This open-label, single arm study enrolled current reusable soft toric lens wearers with minimum score of 12 on the contact lens dry eye (CLDEQ-8) questionnaire. Subjects were also administered the CLDEQ-8 after 1 replacement schedule of their optimized habitual toric lenses (2 to 4 weeks), and after 2 weeks of wear with delefilcon A toric daily disposable lenses (Dailies Total1 for Astigmatism; Alcon Vision LLC, Fort Worth, Texas).

Results

A total of 85 subjects completed the study. Mean total CLDEQ-8 score was 16.8 ± 8.1 for subjects refit with their optimized habitual toric lenses and 12.4 ± 7.5 for subjects refit with delefilcon A toric lenses, a difference of 4.3 ± 10.4 (p < 0.001). With delefilcon A toric lenses, 78.9% of subjects reported little to no intensity of eye discomfort, compared to 51.7% for the habitual toric lenses (p = 0.005). In addition, 77.7% of subjects reported little to no intensity of dryness for delefilcon A toric lenses, compared to 50.6% for the habitual toric lenses (p = 0.001).

Conclusion

The subjective comfort in symptomatic habitual reusable toric contact lens wearers was improved by refitting with delefilcon A toric lenses.

Plain Language Summary

Discomfort while wearing contact lenses is often a reason why patients decide to stop wearing their lenses. There are many different contact lens materials to choose from, and each may affect discomfort differently. The replacement schedule of a contact lens may also be a factor for discomfort, with lenses replaced daily (daily disposables) offering advantages over those replaced weekly or monthly (frequent replacement). The purpose of this study was to subjectively evaluate comfort with a new daily disposable toric contact lens. The results of this study suggest that subjective comfort in symptomatic habitual reusable toric contact lens wearers was improved by refitting with a new daily disposable toric lens.

Keywords:

• comfort
• toric
• contact lens
• delefilcon A
• Dailies Total1 for Astigmatism

Disclosure

Brad Hall reports that he has received consulting fees from Ace Vision Group outside the submitted work. The authors report no other conflict of interest for this work.

Additional information

Funding

This study was supported with an investigator-initiated study grant (72144855) from Alcon Vision, LLC, Fort Worth, TX.