Topography-Guided LASIK: A Prospective Study Evaluating Patient-Reported Outcomes

Abstract

Purpose

To evaluate patient-reported outcomes with a validated patient questionnaire following topography-guided LASIK (TG-LASIK).

Methods

Patients undergoing TG-LASIK using Phorcides analytic software were prospectively enrolled to receive an adapted Patient-Reported Outcomes with LASIK Symptoms and Satisfaction (PROWL) questionnaire before and 26-weeks after treatment. The main study outcome was the change in the Global Vision Satisfaction Index from the PROWL questionnaire.

Results

Forty-six patients underwent treatment and completed the modified PROWL questionnaire before and 26-weeks after TG-LASIK. The Global Vision Satisfaction Index from the modified PROWL questionnaire improved from 4.07 (3.87–4.26) to 5.00 (4.81–5.19) after the TG-LASIK treatment (p < 0.0001). The study population’s binocular uncorrected distance visual acuity was 20/16, 20/12.5, and 20/10 or better in 100%, 87.0%, and 15.2% at 26 weeks post TG-LASIK, respectively.

Conclusion

Patient satisfaction as assessed with the modified PROWL questionnaire is very high after undergoing TG-LASIK using Phorcides analytic software. Patient-reported outcomes add another dimension when assessing treatment efficacy beyond change in visual acuity and corneal architecture, and specialists may consider incorporating such assessments into the consenting process and patient education at large.

Keywords:

• LASIK
• topography-guided
• Contoura
• PROWL
• patient-reported outcomes
• Phorcides

Abbreviations

TG-LASIK, topography-guided laser in situ keratomileusis; WFO-LASIK, wavefront optimized laser in situ keratomileusis; WG-LASIK, wavefront-guided laser in situ keratomileusis; CDVA, best-corrected distance visual acuity; UDVA, uncorrected distance visual acuity; HOA, higher order aberrations; PROWL, patient-reported outcomes with LASIK; OSI, Objective Scatter Index.

Data Sharing Statement

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

Ethics Statement

The study was approved by the Salus Independent Review Board (IORG0005674-1, Austin, TX, USA) in accordance with the Ethical Standards laid down in the Declaration of Helsinki.

Acknowledgments

This study was presented at the 2023 ASCRS meeting during a paper session.

Author Contributions

All authors made substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data; took part in drafting the article or revising it critically for important intellectual content; agreed to submit to the current journal; gave final approval of the version to be published; and agreed to be accountable for all aspects of the work.

Disclosure

The authors report no conflicts of interest in this works.

Additional information

Funding

The Alcon Foundation (Alcon Vision, LLC; Fort Worth, TX, USA) provided a research grant for this study.