Abstract
Purpose
To characterize corneal biomechanical properties using the CORVIS-ST device in myopic individuals.
Methods
This prospective cross-sectional study included patients with myopia. Our study included 154 eyes of 154 myopic patients aged between 18 and 40 years, with stable refraction for at least 2 years. A full ophthalmological examination and corneal tomography were performed using a Pentacam HR device. Corneal biomechanical parameters were assessed using the CORVIS-ST device in mild, moderate, severe, and extreme myopia groups.
Results
Statistically significant differences were observed in the DA ratio (p = 0.033), SP-A (p=0.009), CBI (p=0.041), SSI (p=0.000), and Peak distance (p = 0.032). In correlation with different Corvis ST biomechanical variables, SE was found to be correlated with DA ratio(r=−0.191, p=0.018), SP-A(r=0.199, p=0.013) and SSI(r=−0.336, p=0.000), while in multiple regression analysis, SE was found to be independently correlated with SSI and peak distance(p=0.036,0.038 respectively) while the grade of myopia was found to be independently correlated with SP-A(p=0.034).
Conclusion
SSI, Peak distance, and SP-A were independently related to SE and myopia grade, confirming the hypothesis that eyes with higher myopia are more deformable and less stress resistant.
Data Sharing Statement
The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.
Ethical Statement
This study was approved by the Central Scientific Research Ethical Committee Board of the High Council of University Hospitals number NO-0332[V2] and adhered to the Helsinki Declaration. Written informed consent was obtained from all the patients.
Disclosure
No conflict of interest for any of the authors.