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Joseph V. Pergolizzi, Franklin Breve, Peter Magnusson, JoAnn K. LeQuang & Guistino Varassi. (2023) Current and emerging COX inhibitors for treating postoperative pain following oral surgery. Expert Opinion on Pharmacotherapy 24:3, pages 347-358.
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Joseph V. Pergolizzi$suffix/text()$suffix/text(), Christopher Gharibo, Peter Magnusson, Frank Breve, Jo Ann LeQuang & Giustino Varrassi. (2022) Pharmacotherapeutic management of trigeminal neuropathic pain: an update. Expert Opinion on Pharmacotherapy 23:10, pages 1155-1164.
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Giustino Varrassi. (2020) Pain and postgraduate medicine. Postgraduate Medicine 132:sup3, pages 1-2.
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Joseph V. Pergolizzi$suffix/text()$suffix/text(), Peter Magnusson, Robert B. Raffa, Jo Ann LeQuang & Flaminia Coluzzi. (2020) Developments in combined analgesic regimens for improved safety in postoperative pain management. Expert Review of Neurotherapeutics 20:9, pages 981-990.
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Carmen Almansa, Christopher S Frampton, José Miguel Vela, Steve Whitelock & Carlos R Plata-Salamán. (2019) Co-crystals as a new approach to multimodal analgesia and the treatment of pain. Journal of Pain Research 12, pages 2679-2689.
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Thalita Martins da Silva, Marcelo Gomes Davanço, Jessica Meulman, Débora Renz Barreto Vianna, Fernando Costa, Fernando Bastos Canton Pacheco, Silvana Aparecida Calafatti Carandina, Eduardo Issa & Celso Francisco Pimentel Vespasiano. (2024) Tramadol/Diclofenac Fixed‐Dose Combination for Acute Pain Management: Bioavailability Assessment of a Generic Product. Clinical Pharmacology in Drug Development.
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George A Macheras, Dimitrios Tzefronis, Chrysoula Argyrou, Elena Nikolakopoulou, Alejandro Gálvez Miravete & Thefilos S Karachalios. (2024) Pain management after total hip arthroplasty: comparative study of analgesic efficacy and tolerability between oral tramadol/dexketoprofen and injectable paracetamol + tramadol. HIP International 34:3, pages 304-310.
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Kok Yuen Ho, Bibek Gyanwali, Cesar Dimayuga, Edgar Michael Eufemio, Edwin Bernardo, Gopinathan Raju, Keen Wai Chong, Kritsadakorn Waithayayothin, Leonardo Ona, Marc Anthony L Castro, Passakorn Sawaddiruk, Roehl C Salvador, Sharifah Ahmad Roohi, Suwimon Tangwiwat, Vajara Wilairatana, Zhi Hao Oon, Ankur Gupta & Dinesh Nagrale. (2024) REKOVER study protocol: a pRospective patient treatment rEgistry of tramadol and dexKetoprofen trometamol oral fixed-dose combination (SKUDEXA) in mOderate to seVere acutE pain in Real-world setting in Asia. BMJ Open 14:3, pages e080620.
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Antonella Paladini, Christopher Gharibo, Sonia Khalbous, Ammar Salti, Tolga Ergönenç, Alberto Pasqualucci & Giustino Varrassi. (2023) Looking Back, Moving Forward in Pain Medicine. Cureus.
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Antonella Paladini, Narinder Rawal, Miquel Coca Martinez, Mehdi Trifa, Antonio Montero, Joseph Pergolizzi, Alberto Pasqualucci, Marco Antonio Narvaez Tamayo, Giustino Varrassi & Oscar De Leon Casasola. (2023) Advances in the Management of Acute Postsurgical Pain: A Review. Cureus.
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Andrea Aramini, Gianluca Bianchini, Samuele Lillini, Mara Tomassetti, Niccolò Pacchiarotti, Daniele Canestrari, Pasquale Cocchiaro, Rubina Novelli, Maria Concetta Dragani, Ferdinando Palmerio, Simone Mattioli, Simone Bordignon, Michele d’Angelo, Vanessa Castelli, Francesco d’Egidio, Sabatino Maione, Livio Luongo, Serena Boccella, Annamaria Cimini, Laura Brandolini, Michele Remo Chierotti & Marcello Allegretti. (2023) Ketoprofen, lysine and gabapentin co-crystal magnifies synergistic efficacy and tolerability of the constituent drugs: Pre-clinical evidences towards an innovative therapeutic approach for neuroinflammatory pain. Biomedicine & Pharmacotherapy 163, pages 114845.
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Saran Tantavisut, Kok Yuen Ho, Edsel F Arandia, Sze Chung Cheng, Sarasate Eiamtanasate, Rahat Jarayabhand, Raymond Alvin J Kokseng, Jesse Jane L Paco, Gopinathan Raju, Prakrit Suwanpramote, Marvin Thepsoparn & Dinesh Nagrale. (2023) Real-World Evidence on the Efficacy and Tolerability of Tramadol/Dexketoprofen (TRAM/DKP) Fixed-Dose Combination for the Management of Acute Non-surgical Pain in Asian Patients: A Multicentre Retrospective Case Series. Cureus.
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Amr M. Elnaghy, Alaa H. Elshazli, Amany E. Badr & Shaymaa E. Elsaka. (2022) Effect of preoperative tramadol, ibuprofen, ibuprofen/acetaminophen on the anaesthetic efficacy of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis. Australian Endodontic Journal 49:1, pages 165-173.
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Magdi Hanna, Serge Perrot & Giustino Varrassi. (2023) Critical Appraisal of Current Acute LBP Management and the Role of a Multimodal Analgesia: A Narrative Review. Pain and Therapy 12:2, pages 377-398.
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Jeffrey Tuan, Edward H Wang, Jose Rhoel C De Leon, Marvin Jonne Mendoza & Giustino Varrassi. (2023) Management of Acute Cancer Pain in Asia: An Expert Opinion on the Role of Tramadol/Dexketoprofen Fixed-Dose Combination. Cureus.
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. (2022) Meloxicam is the Primary Choice of Analgesic for Dogs and Cats; A Cross-Sectional Clinical Study in Bangladesh. International Journal of Agriculture and Veterinary Sciences, pages 86-93.
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Giustino Varrassi, Magdi Hanna, Stefano Coaccioli, Meto Suada & Serge Perrot. (2022) DANTE Study: The First Randomized, Double-Blind, Placebo and Active-Controlled, Parallel Arm Group Study Evaluating the Analgesic Efficacy and Safety of Dexketoprofen TrometAmol aNd Tramadol Hydrochloride Oral FixEd Dose Combination on Moderate to Severe Acute Pain in Patients with Acute Low Back Pain—Rationale and Design. Pain and Therapy 11:3, pages 1055-1070.
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Pablo Castroman, Ovelio Quiroga, Victor Mayoral Rojals, Maria Gómez, Eleni Moka, Joseph Pergolizzi Jr & Giustino Varrassi. (2022) Reimagining How We Treat Acute Pain: A Narrative Review. Cureus.
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Maria Gómez, Cesar E Izquierdo, Victor Mayoral Rojals, Joseph Pergolizzi Jr, Ricardo Plancarte Sanchez, Antonella Paladini & Giustino Varrassi. (2022) Considerations for Better Management of Postoperative Pain in Light of Chronic Postoperative Pain: A Narrative Review. Cureus.
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Augustine Tandoh, Cynthia Amaning Danquah, Charles Kwaku Benneh, Donatus Wewura Adongo, Eric Boakye-Gyasi & Eric Woode. (2022) Effect of Diclofenac and Andrographolide Combination on Carrageenan-Induced Paw Edema and Hyperalgesia in Rats. Dose-Response 20:2, pages 155932582211038.
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Victor Mayoral Rojals, Moises Charaja, Oscar De Leon Casasola, Antonio Montero, Marco Antonio Narvaez Tamayo & Giustino Varrassi. (2022) New Insights Into the Pharmacological Management of Postoperative Pain: A Narrative Review. Cureus.
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Enrique Orrillo, Luis Vidal Neira, Fabián Piedimonte, Ricardo Plancarte Sanchez, Smiljan Astudilllo Mihovilovic, Marco Antonio Narvaez Tamayo, Martina Rekatsina & Giustino Varrassi. (2022) What Is New in the Clinical Management of Low Back Pain: A Narrative Review. Cureus.
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Dimos-Dimitrios Mitsikostas, Eleni Moka, Enrique Orrillo, Caterina Aurilio, Athina Vadalouca, Antonella Paladini & Giustino Varrassi. (2022) Neuropathic Pain in Neurologic Disorders: A Narrative Review. Cureus.
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Antonio Montero Matamala, Magdi Hanna, Serge Perrot & Giustino Varrassi. (2022) Avoid Postoperative Pain To Prevent Its Chronification: A Narrative Review. Cureus.
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A.V. Amelin, V.A. Balyazin, O.S. Davydov, S.K. Zyryanov, D.V. Kiselev, O.V. Kurushina, L.A. Medvedeva, N.M. Tereshchenko, V.A. Shirokov, M.L. Kukushkin & N.N. Yakhno. (2022) Russian multicenter study of fixed combination of diclofenac and orphenadrine its efficacy and tolerance of in acute non-specific pain and radiculopathy relief. Russian Journal of Pain 20:1, pages 33.
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Giorgia Saltelli, Antonella Paladini, Martina Rekatsina & Giustino Varrassi. 2022. The Neurobiology, Physiology, and Psychology of Pain. The Neurobiology, Physiology, and Psychology of Pain
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Marcos Aurélio Teixeira, Juliana Zampoli Boava Papini, Aguinaldo Garcez & Giovana Radomille Tofoli. (2021) Comparative analysis of two laser wavelengths in the stimulation of acupuncture points for analgesic effects in an animal model. Journal of Biophotonics 15:1.
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Ameer Hamza Rabbani, Qudrat Ullah, Omer Naseer, Faizan Haider Gardezi, Muhammad Shahid, Kashif Hussain, Taimoor Saleem, Ahmad Ali, Yasir Razzaq Khan & Abdul Waheed. (2021) Comparative Multimodal Palliative efficacy of gabapentin and tramadol By Using Two Pain Scoring Systems in Cats Undergoing Ovariohysterectomy. Acta Veterinaria 71:4, pages 417-434.
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CRISTINA VALLECILLO, MARTA VALLECILLO-RIVAS, RAFAEL GÁLVEZ, MANUEL VALLECILLO-CAPILLA & MARÍA VICTORIA OLMEDO-GAYA. (2021) ANALGESIC EFFICACY OF TRAMADOL/DEXKETOPROFEN VS IBUPROFEN AFTER IMPACTED LOWER THIRD MOLAR EXTRACTION: A RANDOMIZED CONTROLLED CLINICAL TRIAL. Journal of Evidence Based Dental Practice 21:4, pages 101618.
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Amany E. Ayad, Ossama H. Salman, Ahmed Mokhtar Fathy Ibrahim, Waleed A. M. Al-Taher, Adel M. Mishriky, Joseph V. Pergolizzi, Omar Viswanath, Ivan Urits, Martina Rekatsina, John F. Peppin, Antonella Paladini & Giustino Varrassi. (2021) Influences of Gender on Intravenous Nalbuphine Actions After Major Abdominal Surgery: A Multicenter Study. Pain and Therapy 10:2, pages 1215-1233.
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Joseph V. PergolizziJrJr, Peter Magnusson, Paul J. Christo, Jo Ann LeQuang, Frank Breve, Kailyn Mitchell & Giustino Varrassi. (2021) Opioid Therapy in Cancer Patients and Survivors at Risk of Addiction, Misuse or Complex Dependency. Frontiers in Pain Research 2.
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Magdi Hanna, Antonio Montero, Serge Perrot & Giustino Varrassi. (2021) Tramadol/Dexketoprofen Analgesic Efficacy Compared with Tramadol/Paracetamol in Moderate to Severe Postoperative Acute Pain: Subgroup Analysis of a Randomized, Double-Blind, Parallel Group Trial—DAVID Study. Pain and Therapy 10:1, pages 485-503.
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Juan Carlos Flores-Arriaga, Daniel Chavarría-Bolaños, Amaury de Jesús Pozos-Guillén, Vladimir Alonso Escobar-Barrios & Bernardino Isaac Cerda-Cristerna. (2021) Synthesis of a PVA drug delivery system for controlled release of a Tramadol–Dexketoprofen combination. Journal of Materials Science: Materials in Medicine 32:5.
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Antonella Paladini & Giustino Varrassi. 2021. Pain Management - Practices, Novel Therapies and Bioactives. Pain Management - Practices, Novel Therapies and Bioactives.
Islam Mohammad Shehata, Sabri Barsoumv, Amir Elhass, Giustino Varrassi, Antonella Paladini, Dariusz Myrcik, Ivan Urits, Alan D Kaye & Omar Viswanath. (2021) Anesthetic Considerations for Cesarean Delivery After Uterine Transplant. Cureus.
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M.L. Kukushkin, A.V. Amelin, S.K. Zyryanov, V.A. Balyazin, V.A. Shirokov, L.A. Medvedeva, L.R. Akhmadeeva, O.V. Kurushina, D.V. Kiselev, G.R. Abuzarova & O.S. Davydov. (2021) Expert council resolution on the intermediate results of statistical study «Effectiveness of a fixed combination of orphenadrine and diclofenac in patients with acute back and neck pain». Russian Journal of Pain 19:2, pages 60.
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Chen-Chen Ji, Bo Liu, Yi-Jie Shao, Ting Liang, Hua-Ye Jiang, Guang-Dong Chen & Zong-Ping Luo. (2020) Microstructure and mechanical properties of subchondral bone are negatively regulated by tramadol in osteoarthritis in mice. Bioscience Reports 40:9.
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Giustino Varrassi, Cheng Teng Yeam, Martina Rekatsina, Joseph V. Pergolizzi, Panagiotis Zis & Antonella Paladini. (2020) The Expanding Role of the COX Inhibitor/Opioid Receptor Agonist Combination in the Management of Pain. Drugs 80:14, pages 1443-1453.
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Martina Rekatsina, Antonella Paladini, Alba Piroli, Panagiotis Zis, Joseph V. Pergolizzi & Giustino Varrassi. (2020) Pathophysiologic Approach to Pain Therapy for Complex Pain Entities: A Narrative Review. Pain and Therapy 9:1, pages 7-21.
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E. A. Ushkalova, S. K. Zyryanov & K. E. Zatolochina. (2020) The fixed combination of diclofenac and orphenadrine in the treatment of acute pain syndromes. Neurology, Neuropsychiatry, Psychosomatics 12:1, pages 100-104.
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Giustino Varrassi, Joseph Pergolizzi, John F. Peppin & Antonella Paladini. 2020. Brain and Heart Dynamics. Brain and Heart Dynamics
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Giustino Varrassi, Stefano Coaccioli, Josè De-Andrés, Magdi Hanna, Giorgos Macheras, Antonio Montero, Serge Perrot, Vincenzo Piras & Carmelo Scarpignato. (2019) Expert Consensus on Clinical Use of an Orally Administered Dexketoprofen Plus Tramadol Fixed-Dose Combination in Moderate-To-Severe Acute Pain: A Delphi Study. Advances in Therapy 36:11, pages 3174-3185.
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Giustino Varrassi, Eli Alon, Michela Bagnasco, Luigi Lanata, Victor Mayoral-Rojals, Antonella Paladini, Joseph V. Pergolizzi, Serge Perrot, Carmelo Scarpignato & Thomas Tölle. (2019) Towards an Effective and Safe Treatment of Inflammatory Pain: A Delphi-Guided Expert Consensus. Advances in Therapy 36:10, pages 2618-2637.
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Ahmed Barakat. (2019) Revisiting Tramadol: A Multi-Modal Agent for Pain Management. CNS Drugs 33:5, pages 481-501.
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Willias Masocha & Amal Thomas. (2019) Indomethacin plus minocycline coadministration relieves chemotherapy and antiretroviral drug-induced neuropathic pain in a cannabinoid receptors-dependent manner. Journal of Pharmacological Sciences 139:4, pages 325-332.
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Cosme Gay-Escoda, Magdi Hanna, Antonio Montero, Thomas Dietrich, Stefano Milleri, Ewa Giergiel, Tóth Bagi Zoltán & Giustino Varrassi. (2019) Tramadol/dexketoprofen (TRAM/DKP) compared with tramadol/paracetamol in moderate to severe acute pain: results of a randomised, double-blind, placebo and active-controlled, parallel group trial in the impacted third molar extraction pain model (DAVID study). BMJ Open 9:2, pages e023715.
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Hugo F. Miranda, Fernando Sierralta, Nicolas Aranda, Paula Poblete, Viviana Noriega & Juan C. Prieto. (2018) Synergism between gabapentin–tramadol in experimental diabetic neuropathic pain. Fundamental & Clinical Pharmacology 32:6, pages 581-588.
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Giustino Varrassi, Mariella Fusco, Stephen D. Skaper, Daniele Battelli, Panagiotis Zis, Stefano Coaccioli, Maria Caterina Pace & Antonella Paladini. (2018) A Pharmacological Rationale to Reduce the Incidence of Opioid Induced Tolerance and Hyperalgesia: A Review. Pain and Therapy 7:1, pages 59-75.
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