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Read on this site (11)
Gary L. Diamond, Nicholas P. Skoulis, A. Robert Jeffcoat & J Frank Nash. (2021) A Physiological-Based Pharmacokinetic Model For The Broad Spectrum Antimicrobial Zinc Pyrithione: II. Dermal Absorption And Dosimetry In The Rat. Journal of Toxicology and Environmental Health, Part A 84:15, pages 609-631.
Read now
Read now
Sinthyia Ahmed, Nazrul Islam, Md Shahinozzaman, Sayo O. Fakayode, Nadia Afrin & Mohammad A. Halim. (2021) Virtual screening, molecular dynamics, density functional theory and quantitative structure activity relationship studies to design peroxisome proliferator-activated receptor-γ agonists as anti-diabetic drugs. Journal of Biomolecular Structure and Dynamics 39:2, pages 728-742.
Read now
Read now
Kenneth T. Bogen & Ankur Singhal. (2017) Malathion dermal permeability in relation to dermal load: Assessment by physiologically based pharmacokinetic modeling of in vivo human data. Journal of Environmental Science and Health, Part B 52:2, pages 138-146.
Read now
Read now
Gary L. Diamond, Nicholas P. Skoulis, A. Robert Jeffcoat & J. Frank Nash. (2017) A physiologically based pharmacokinetic model for the broad-spectrum antimicrobial zinc pyrithione: I. Development and verification. Journal of Toxicology and Environmental Health, Part A 80:2, pages 69-90.
Read now
Read now
J.B. Veselinović, G.M. Nikolić, N.V. Trutić, J.V. Živković & A.M. Veselinović. (2015) Monte Carlo QSAR models for predicting organophosphate inhibition of acetycholinesterase . SAR and QSAR in Environmental Research 26:6, pages 449-460.
Read now
Read now
T. Peyret & K. Krishnan. (2011) QSARs for PBPK modelling of environmental contaminants. SAR and QSAR in Environmental Research 22:1-2, pages 129-169.
Read now
Read now
K. Price & K. Krishnan. (2011) An integrated QSAR–PBPK modelling approach for predicting the inhalation toxicokinetics of mixtures of volatile organic chemicals in the rat. SAR and QSAR in Environmental Research 22:1-2, pages 107-128.
Read now
Read now
Christopher
D. Ruark, C.
Eric Hack, Peter
J. Robinson & Jeffery
M. Gearhart. (2010) Quantitative Structure–Activity Relationships for Organophosphates Binding to Trypsin and Chymotrypsin. Journal of Toxicology and Environmental Health, Part A 74:1, pages 1-23.
Read now
Read now
Elaine
A. Cohen Hubal, Ann Richard, Lesa Aylward, Steve Edwards, Jane Gallagher, Michael-Rock Goldsmith, Sastry Isukapalli, Rogelio Tornero-Velez, Eric Weber & Robert Kavlock. (2010) Advancing Exposure Characterization for Chemical Evaluation and Risk Assessment. Journal of Toxicology and Environmental Health, Part B 13:2-4, pages 299-313.
Read now
Read now
S. Lee, A. L. Busby, C. Timchalk & T. S. Poet. (2008) Effects of Nicotine Exposure on In Vitro Metabolism of Chlorpyrifos in Male Sprague-Dawley Rats. Journal of Toxicology and Environmental Health, Part A 72:2, pages 74-82.
Read now
Read now
RichardP. Moody, Mohammed Akram, Eva Dickson & Ih Chu. (2007) In Vitro Dermal Absorption of Methyl Salicylate, Ethyl Parathion, and Malathion: First Responder Safety. Journal of Toxicology and Environmental Health, Part A 70:12, pages 985-999.
Read now
Read now
Articles from other publishers (38)
Shensheng Zhao, Sebastiaan Wesseling, Ivonne. M. C. M. Rietjens & Marije Strikwold. (2022) Inter-individual variation in chlorpyrifos toxicokinetics characterized by physiologically based kinetic (PBK) and Monte Carlo simulation comparing human liver microsome and Supersome™ cytochromes P450 (CYP)-specific kinetic data as model input. Archives of Toxicology 96:5, pages 1387-1409.
Crossref
Crossref
V. Kumar, Deepika Deepika & R. P. Sharma. 2020. Challenges in Endocrine Disruptor Toxicology and Risk Assessment. Challenges in Endocrine Disruptor Toxicology and Risk Assessment
80
120
.
Jeffery M. Gearhart, Peter J. Robinson & Edward M. Jakubowski. 2020. Handbook of Toxicology of Chemical Warfare Agents. Handbook of Toxicology of Chemical Warfare Agents
945
952
.
Samantha L. Rumschlag, Neal T. Halstead, Jason T. Hoverman, Thomas R. Raffel, Hunter J. Carrick, Peter J. Hudson & Jason R. Rohr. (2019) Effects of pesticides on exposure and susceptibility to parasites can be generalised to pesticide class and type in aquatic communities. Ecology Letters 22:6, pages 962-972.
Crossref
Crossref
Anteneh Desalegn, Stephanie Bopp, David Asturiol, Lara Lamon, Andrew Worth & Alicia Paini. (2019) Role of Physiologically Based Kinetic modelling in addressing environmental chemical mixtures – A review. Computational Toxicology 10, pages 158-168.
Crossref
Crossref
Anna H. C. Vlot, Wilhelmus E. A. de Witte, Meindert Danhof, Piet H. van der Graaf, Gerard J. P. van Westen & Elizabeth C. M. de Lange. (2017) Target and Tissue Selectivity Prediction by Integrated Mechanistic Pharmacokinetic-Target Binding and Quantitative Structure Activity Modeling. The AAPS Journal 20:1.
Crossref
Crossref
Carey Pope, Kirstin Hester & Lester Sultatos. 2018.
Dimosthenis Α. Sarigiannis, Krystalia Papadaki, Periklis Kontoroupis & Spyros P. Karakitsios. (2017) Development of QSARs for parameterizing Physiology Based ToxicoKinetic models. Food and Chemical Toxicology 106, pages 114-124.
Crossref
Crossref
Ni Ai, Xiaohui Fan & Sean Ekins. (2015) In silico methods for predicting drug–drug interactions with cytochrome P-450s, transporters and beyond. Advanced Drug Delivery Reviews 86, pages 46-60.
Crossref
Crossref
Jeffery M. Gearhart, Peter J. Robinson & Edward M. Jakubowski. 2015. Handbook of Toxicology of Chemical Warfare Agents. Handbook of Toxicology of Chemical Warfare Agents
875
882
.
. (2014) Modern methodologies and tools for human hazard assessment of chemicals. EFSA Journal 12:4.
Crossref
Crossref
Jinsong Zhao & Shuxia Yu. (2013) Quantitative structure–activity relationship of organophosphate compounds based on molecular interaction fields descriptors. Environmental Toxicology and Pharmacology 35:2, pages 228-234.
Crossref
Crossref
Jae Hyoun Kim. (2012) Is it Possible to Predict the ADI of Pesticides using the QSAR Approach?. Korean Journal of Environmental Health Sciences 38:6, pages 550-560.
Crossref
Crossref
Abby A. Li, Tina E. Levine, Carol J. Burns & W. Kent Anger. (2012) Integration of epidemiology and animal neurotoxicity data for risk assessment. NeuroToxicology 33:4, pages 823-832.
Crossref
Crossref
Corie A. Ellison, Alice L. Crane & James R. Olson. 2012. Metabolism of Drugs and Other Xenobiotics. Metabolism of Drugs and Other Xenobiotics
685
702
.
Alice L. Crane, Kathrin Klein, Ulrich M. Zanger & James R. Olson. (2012) Effect of CYP2B6*6 and CYP2C19*2 genotype on chlorpyrifos metabolism. Toxicology 293:1-3, pages 115-122.
Crossref
Crossref
Nina Ching Y. Wang, Glenn E. Rice, Linda K. Teuschler, Joan Colman & Raymond S. H. Yang. (2012)
An
In Silico
Approach for Evaluating a Fraction-Based, Risk Assessment Method for Total Petroleum Hydrocarbon Mixtures
. Journal of Toxicology 2012, pages 1-8.
Crossref
Crossref
Corie A. Ellison, Yuan Tian, James B. Knaak, Paul J. Kostyniak & James R. Olson. (2012) Human Hepatic Cytochrome P450-Specific Metabolism of the Organophosphorus Pesticides Methyl Parathion and Diazinon. Drug Metabolism and Disposition 40:1, pages 1-5.
Crossref
Crossref
M. R. Goldsmith, J. C. Johnson, D. T. Chang, R. Tornero-Velez, J. B. Knaak & Curtis C. Dary. 2012. Parameters for Pesticide QSAR and PBPK/PD Models for Human Risk Assessment. Parameters for Pesticide QSAR and PBPK/PD Models for Human Risk Assessment
3
15
.
James B. Knaak, Cecilla Tan & Curt C. Dary. 2012. Toxicology and Human Environments. Toxicology and Human Environments
117
162
.
James B. Knaak, Curtis C. Dary, Xiaofei Zhang, Robert W. Gerlach, R. Tornero-Velez, Daniel T. Chang, Rocky Goldsmith & Jerry N. Blancato. 2012. Reviews of Environmental Contamination and Toxicology. Reviews of Environmental Contamination and Toxicology
1
114
.
Amit Kumar Sharma, Karuna Gaur, Rajeev Kumar Tiwari & Mulayam Singh Gaur. (2011) Computational interaction analysis of organophosphorus pesticides with different metabolic proteins in humans. Journal of Biomedical Research 25:5, pages 335-347.
Crossref
Crossref
Robert J. Foxenberg, Corie A. Ellison, James B. Knaak, Changxing Ma & James R. Olson. (2011) Cytochrome P450-specific human PBPK/PD models for the organophosphorus pesticides: Chlorpyrifos and parathion. Toxicology 285:1-2, pages 57-66.
Crossref
Crossref
Charles Timchalk. 2011. Anticholinesterase Pesticides. Anticholinesterase Pesticides
267
287
.
Charles Timchalk, Paul M. Hinderliter & Torka S. Poet. 2010. Quantitative Modeling in Toxicology. Quantitative Modeling in Toxicology
135
165
.
Xiaofei Zhang, James B. Knaak, Rogelio Tornero-Velez, Jerry N. Blancato & Curtis C. Dary. 2010. Hayes' Handbook of Pesticide Toxicology. Hayes' Handbook of Pesticide Toxicology
1591
1605
.
M. Eddleston, F. Worek, P. Eyer, H. Thiermann, L. Von Meyer, K. Jeganathan, M. H. R. Sheriff, A. H. Dawson & N. A. Buckley. (2009) Poisoning with the S-Alkyl organophosphorus insecticides profenofos and prothiofos. QJM 102:11, pages 785-792.
Crossref
Crossref
Kazuhiko Mochida, Katsutoshi Ito, Hiroya Harino, Hiroyuki Tanaka, Toshimitsu Onduka, Akira Kakuno & Kazunori Fujii. (2009) Inhibition of acetylcholinesterase by metabolites of copper pyrithione (CuPT) and its possible involvement in vertebral deformity of a CuPT-exposed marine teleostean fish. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 149:4, pages 624-630.
Crossref
Crossref
Allan S. Felsot. 2009. Information Resources in Toxicology. Information Resources in Toxicology
151
165
.
Jinghai J. Xu, Sean Ekins, Michael Mcglashen & Douglas Lauffenburger. 2008. Drug Efficacy, Safety, and Biologics Discovery. Drug Efficacy, Safety, and Biologics Discovery
349
379
.
Guido Mastrantonio, Hans-Georg Mack & Carlos Omar Della Védova. (2008) Interpretation of the mechanism of acetylcholinesterase inhibition ability by organophosphorus compounds through a new conformational descriptor. an experimental and theoretical study. Journal of Molecular Modeling 14:9, pages 813-821.
Crossref
Crossref
James B. Knaak, Curt C. Dary, Miles S. Okino, Fred W. Power, Xiaofei Zhang, Carol B. Thompson, R. Tornero-Velez & Jerry N. Blancato. 2008. Reviews of Environmental Contamination and Toxicology. Reviews of Environmental Contamination and Toxicology
53
212
.
Charles Timchalk, Ahmed A. Kousba & Torka S. Poet. (2007) An Age-Dependent Physiologically Based Pharmacokinetic/Pharmacodynamic Model for the Organophosphorus Insecticide Chlorpyrifos in the Preweanling Rat. Toxicological Sciences 98:2, pages 348-365.
Crossref
Crossref
Robert J. Foxenberg, Barbara P. McGarrigle, James B. Knaak, Paul J. Kostyniak & James R. Olson. (2007) Human Hepatic Cytochrome P450-Specific Metabolism of Parathion and Chlorpyrifos. Drug Metabolism and Disposition 35:2, pages 189-193.
Crossref
Crossref
Larry J. Jolivette & Sean Ekins. 2007.
131
176
.
C. Timchalk, T.S. Poet & A.A. Kousba. (2006) Age-dependent pharmacokinetic and pharmacodynamic response in preweanling rats following oral exposure to the organophosphorus insecticide chlorpyrifos. Toxicology 220:1, pages 13-25.
Crossref
Crossref
Jian-Xin Guo, Jay J.-Q. Wu, Jeffery B. Wright & Gerald H. Lushington. (2006) Mechanistic Insight into Acetylcholinesterase Inhibition and Acute Toxicity of Organophosphorus Compounds: A Molecular Modeling Study. Chemical Research in Toxicology 19:2, pages 209-216.
Crossref
Crossref
Charles Timchalk. 2006. Toxicology of Organophosphate & Carbamate Compounds. Toxicology of Organophosphate & Carbamate Compounds
103
125
.