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Eileen D. Kuempel, Lisa M. Sweeney, John B. Morris & Annie M. Jarabek. (2015) Advances in Inhalation Dosimetry Models and Methods for Occupational Risk Assessment and Exposure Limit Derivation. Journal of Occupational and Environmental Hygiene 12:sup1, pages S18-S40.
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M. Moiz Mumtaz, Meredith Ray, Susan
R. Crowell, Deborah Keys, Jeffrey Fisher & Patricia Ruiz. (2012) Translational Research to Develop a Human PBPK Models Tool Kit—Volatile Organic Compounds (VOCs). Journal of Toxicology and Environmental Health, Part A 75:1, pages 6-24.
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Articles from other publishers (35)
Yawen Yuan, Zhihong Li, Ke Wang, Shunguo Zhang, Qingfeng He, Lucy Liu, Zhijia Tang, Xiao Zhu, Ying Chen, Weimin Cai, Chao Peng & Xiaoqiang Xiang. (2023) Pharmacokinetics of Novel Furoxan/Coumarin Hybrids in Rats Using LC-MS/MS Method and Physiologically Based Pharmacokinetic Model. Molecules 28:2, pages 837.
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Styliani Fragki, Aldert H. Piersma, Joost Westerhout, Anne Kienhuis, Nynke I. Kramer & Marco J. Zeilmaker. (2022) Applicability of generic PBK modelling in chemical hazard assessment: A case study with IndusChemFate. Regulatory Toxicology and Pharmacology 136, pages 105267.
Crossref
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David E. Hines, Shannon Bell, Xiaoqing Chang, Kamel Mansouri, David Allen & Nicole Kleinstreuer. (2022) Application of an Accessible Interface for Pharmacokinetic Modeling and In Vitro to In Vivo Extrapolation. Frontiers in Pharmacology 13.
Crossref
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Kannan Krishnan & Sandrine Fleur Chebekoue. 2022. Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology
47
62
.
David E Hines, Jingjie Zhang, Xiaoqing Chang, Shannon M. Bell & K. Monica Lee. (2021) Application of open-source PBPK models in rat-to-human pharmacokinetic extrapolation of oral nicotine exposure. Computational Toxicology 20, pages 100182.
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Crossref
Yawen Yuan, Jun Zhang, Boyu Fang, Xiaoqiang Xiang, Guo Ma, Shunguo Zhang, Bin Zhu & Weimin Cai. (2021) A Novel Method for Predicting the Human Inherent Clearance and Its Application in the Study of the Pharmacokinetics and Drug–Drug Interaction between Azidothymidine and Fluconazole Mediated by UGT Enzyme. Pharmaceutics 13:10, pages 1734.
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Charles Flexner, Andrew Owen, Marco Siccardi & Susan Swindells. (2021) Long-acting drugs and formulations for the treatment and prevention of HIV infection. International Journal of Antimicrobial Agents 57:1, pages 106220.
Crossref
Crossref
V. Kumar, Deepika Deepika & R. P. Sharma. 2020. Challenges in Endocrine Disruptor Toxicology and Risk Assessment. Challenges in Endocrine Disruptor Toxicology and Risk Assessment
80
120
.
Xue Zhang, Qifei Deng, Zhini He, Jie Li, Xiaoju Ma, Zhaorui Zhang, Dehua Wu, Xiumei Xing, Jing Peng, Hongyu Guo, Ming Huang, Liping Chen, Shanfeng Dang, Yanqun Zhu, Zhengbao Zhang, Boyi Yang, Hailan Wang, Wen Chen & Yongmei Xiao. (2020) Influence of benzene exposure, fat content, and their interactions on erythroid-related hematologic parameters in petrochemical workers: a cross-sectional study. BMC Public Health 20:1.
Crossref
Crossref
Dimosthenis Α. Sarigiannis, Spyros P. Karakitsios, Evangelos Handakas & Alberto Gotti. (2020) Development of a generic lifelong physiologically based biokinetic model for exposome studies. Environmental Research 185, pages 109307.
Crossref
Crossref
Jeremy A. Leonard & Yu-Mei Tan. (2019) Tiered approaches for screening and prioritizing chemicals through integration of pharmacokinetics and exposure information with in vitro dose-response data. Computational Toxicology 12, pages 100101.
Crossref
Crossref
L.S. Lautz, R. Oldenkamp, J.L. Dorne & A.M.J. Ragas. (2019) Physiologically based kinetic models for farm animals: Critical review of published models and future perspectives for their use in chemical risk assessment. Toxicology in Vitro 60, pages 61-70.
Crossref
Crossref
Dimosthenis A. Sarigiannis, Spyros Karakitsios, Elena Dominguez-Romero, Krystalia Papadaki, Celine Brochot, Vikas Kumar, Marta Schuhmacher, Moustapha Sy, Hans Mielke, Mathias Greiner, Marcel Mengelers & Martin Scheringer. (2019) Physiology-based toxicokinetic modelling in the frame of the European Human Biomonitoring Initiative. Environmental Research 172, pages 216-230.
Crossref
Crossref
Sandrine F. Chebekoue & Kannan Krishnan. (2019) A framework for application of quantitative property-property relationships (QPPRs) in physiologically based pharmacokinetic (PBPK) models for high-throughput prediction of internal dose of inhaled organic chemicals. Chemosphere 215, pages 634-646.
Crossref
Crossref
Patra Volarath, Yu Zang & Shruti V. Kabadi. 2019. Advances in Computational Toxicology. Advances in Computational Toxicology
233
257
.
Jephthe Jean, Supratik Kar & Jerzy Leszczynski. (2018) QSAR modeling of adipose/blood partition coefficients of Alcohols, PCBs, PBDEs, PCDDs and PAHs: A data gap filling approach. Environment International 121, pages 1193-1203.
Crossref
Crossref
Alie de Boer & Aalt Bast. (2018) Demanding safe foods – Safety testing under the novel food regulation (2015/2283). Trends in Food Science & Technology 72, pages 125-133.
Crossref
Crossref
Dimosthenis A. Sarigiannis, Spyros P. Karakitsios, Evangelos Handakas, Krystalia Papadaki, Dimitris Chapizanis & Alberto Gotti. 2018. Applying Big Data Analytics in Bioinformatics and Medicine. Applying Big Data Analytics in Bioinformatics and Medicine
115
144
.
Kannan Krishnan. 2018. Handbook of Developmental Neurotoxicology. Handbook of Developmental Neurotoxicology
539
557
.
Dimosthenis A. Sarigiannis & Spyros P. Karakitsios. 2018. Chemical Mixtures and Combined Chemical and Nonchemical Stressors. Chemical Mixtures and Combined Chemical and Nonchemical Stressors
81
125
.
Eleni Pefani, Eirini G. Velliou, Nicki Panoskaltsis, Athanasios Mantalaris, Michael C. Georgiadis & Efstratios N. Pistikopoulos. 2017. Modelling Optimization and Control of Biomedical Systems. Modelling Optimization and Control of Biomedical Systems
265
300
.
K.C. Papadaki, S.P. Karakitsios & D.A. Sarigiannis. (2017) Modeling of adipose/blood partition coefficient for environmental chemicals. Food and Chemical Toxicology 110, pages 274-285.
Crossref
Crossref
Dimosthenis Α. Sarigiannis, Krystalia Papadaki, Periklis Kontoroupis & Spyros P. Karakitsios. (2017) Development of QSARs for parameterizing Physiology Based ToxicoKinetic models. Food and Chemical Toxicology 106, pages 114-124.
Crossref
Crossref
Arjun K. ManraiYuxia CuiPierre R. BushelMolly Hall, Spyros Karakitsios, Carolyn J. Mattingly, Marylyn Ritchie, Charles Schmitt, Denis A. Sarigiannis, Duncan C. Thomas, David Wishart, David M. BalshawChirag J. Patel. (2017) Informatics and Data Analytics to Support Exposome-Based Discovery for Public Health. Annual Review of Public Health 38:1, pages 279-294.
Crossref
Crossref
Tom M. Nolte & Ad M. J. Ragas. (2017) A review of quantitative structure–property relationships for the fate of ionizable organic chemicals in water matrices and identification of knowledge gaps. Environmental Science: Processes & Impacts 19:3, pages 221-246.
Crossref
Crossref
Kannan Krishnan & Sandrine Fleur Chebekoue. 2017. Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology
51
65
.
Svava Ósk Jónsdóttir, Trine Klein Reffstrup, Annette Petersen & Elsa Nielsen. (2016) Physicologically Based Toxicokinetic Models of Tebuconazole and Application in Human Risk Assessment. Chemical Research in Toxicology 29:5, pages 715-734.
Crossref
Crossref
Hannu Raunio, Mira Kuusisto, Risto O. Juvonen & Olli T. Pentikäinen. (2015) Modeling of interactions between xenobiotics and cytochrome P450 (CYP) enzymes. Frontiers in Pharmacology 6.
Crossref
Crossref
John Wambaugh. 2015. Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances. Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances
337
361
.
Jos G. Bessems, George Loizou, Kannan Krishnan, Harvey J. ClewellIIIIII, Camilla Bernasconi, Frederic Bois, Sandra Coecke, Eva-Maria Collnot, Walter Diembeck, Lucian Romeo Farcal, Liesbeth Geraets, Ursula Gundert-Remy, Nynke Kramer, Gabriele Küsters, Sofia B. Leite, Olavi R. Pelkonen, Klaus Schröder, Emanuela Testai, Iwona Wilk-Zasadna & José-Manuel Zaldívar-Comenges. (2014) PBTK modelling platforms and parameter estimation tools to enable animal-free risk assessment. Regulatory Toxicology and Pharmacology 68:1, pages 119-139.
Crossref
Crossref
Russell S. Thomas, Martin A. Philbert, Scott S. Auerbach, Barbara A. Wetmore, Michael J. Devito, Ila Cote, J. Craig Rowlands, Maurice P. Whelan, Sean M. Hays, Melvin E. Andersen, M. E. (Bette) Meek, Lawrence W. Reiter, Jason C. Lambert, Harvey J. ClewellIIIIII, Martin L. Stephens, Q. Jay Zhao, Scott C. Wesselkamper, Lynn Flowers, Edward W. Carney, Timothy P. Pastoor, Dan D. Petersen, Carole L. Yauk & Andy Nong. (2013) Incorporating New Technologies Into Toxicity Testing and Risk Assessment: Moving From 21st Century Vision to a Data-Driven Framework. Toxicological Sciences 136:1, pages 4-18.
Crossref
Crossref
Sandra Coecke, Olavi Pelkonen, Sofia Batista Leite, Ulrike Bernauer, Jos GM Bessems, Frederic Y. Bois, Ursula Gundert-Remy, George Loizou, Emanuela Testai & José-Manuel Zaldívar. (2013) Toxicokinetics as a key to the integrated toxicity risk assessment based primarily on non-animal approaches. Toxicology in Vitro 27:5, pages 1570-1577.
Crossref
Crossref
Steve Gutsell & Paul Russell. (2013) The role of chemistry in developing understanding of adverse outcome pathways and their application in risk assessment. Toxicology Research 2:5, pages 299.
Crossref
Crossref
Jane C. Caldwell, Marina V. Evans & Kannan Krishnan. (2012) Cutting Edge PBPK Models and Analyses: Providing the Basis for Future Modeling Efforts and Bridges to Emerging Toxicology Paradigms. Journal of Toxicology 2012, pages 1-10.
Crossref
Crossref
Thomas Peyret & Kannan Krishnan. (2012) Quantitative Property-Property Relationship for Screening-Level Prediction of Intrinsic Clearance of Volatile Organic Chemicals in Rats and Its Integration within PBPK Models to Predict Inhalation Pharmacokinetics in Humans. Journal of Toxicology 2012, pages 1-22.
Crossref
Crossref