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Pharmaceutical Development and Technology Volume 11, 2006 - Issue 4
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Research Article

Impact of Density Gradients on Flow-Through Dissolution in a Cylindrical Flow Cell

Larry E. Stevens Alcon Research, Ltd., Fort Worth, TX, USA
&
Paul J. Missel Alcon Research, Ltd., Fort Worth, TX, USA
Pages 529-534 | Received 14 Dec 2005, Accepted 27 Feb 2006, Published online: 07 Oct 2008

Citations (7)

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Larry E. Stevens, Paul J. Missel & Alan L. Weiner. (2008) Controlled Flow-Through Dissolution Methodology: A High-Performance System. Pharmaceutical Development and Technology 13:2, pages 135-153.
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Articles from other publishers (6)

Marcela Staniszewska, Michał Romański, Justyna Dobosz, Bartosz Kołodziej, Uladzimir Lipski, Grzegorz Garbacz & Dorota Danielak. (2023) PhysioCell — a Novel, Bio-relevant Dissolution Apparatus: Hydrodynamic Conditions and Factors Influencing the Dissolution Dynamics. AAPS PharmSciTech 24:2.
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Deirdre M. D’Arcy, Bo Liu & Owen I. Corrigan. (2011) Investigating the effect of solubility and density gradients on local hydrodynamics and drug dissolution in the USP 4 dissolution apparatus. International Journal of Pharmaceutics 419:1-2, pages 175-185.
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Jesper Østergaard, Fengbin Ye, Jukka Rantanen, Anan Yaghmur, Susan Weng Larsen, Claus Larsen & Henrik Jensen. (2011) Monitoring lidocaine single‐crystal dissolution by ultraviolet imaging. Journal of Pharmaceutical Sciences 100:8, pages 3405-3410.
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Jesper Østergaard, Emil Meng-Lund, Susan Weng Larsen, Claus Larsen, Karsten Petersson, James Lenke & Henrik Jensen. (2010) Real-Time UV Imaging of Nicotine Release from Transdermal Patch. Pharmaceutical Research 27:12, pages 2614-2623.
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Deirdre M. D’Arcy, Bo Liu, Geoff Bradley, Anne Marie Healy & Owen I. Corrigan. (2009) Hydrodynamic and Species Transfer Simulations in the USP 4 Dissolution Apparatus: Considerations for Dissolution in a Low Velocity Pulsing Flow. Pharmaceutical Research 27:2, pages 246-258.
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Deirdre M. D’Arcy, Anne Marie Healy & Owen I. Corrigan. (2009) Towards determining appropriate hydrodynamic conditions for in vitro in vivo correlations using computational fluid dynamics. European Journal of Pharmaceutical Sciences 37:3-4, pages 291-299.
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