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Research Article

Evaluation of Moringa oleifera Aqueous Extract for Antinociceptive and Anti-Inflammatory Activities in Animal Models

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Pages 838-845 | Accepted 18 Apr 2008, Published online: 20 Jan 2009

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Salmon Charles PT Siahaan, Budi Santoso & Widjiati. (2022) Effectiveness of Moringa oleifera Leaves on TNF-α Expression, Insulin Levels, Glucose Levels and Follicle Count in Rattus norvegicus PCOS Model. Diabetes, Metabolic Syndrome and Obesity 15, pages 3255-3270.
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Hafiza Mahreen Mehwish, Muhammad Shahid Riaz Rajoka, Yongai Xiong, Kai Zheng, Haitao Xiao, Tao Anjin, Zhigang Liu, Qinchang Zhu & Zhendan He. (2022) Moringa oleifera – A Functional Food and Its Potential Immunomodulatory Effects. Food Reviews International 38:7, pages 1533-1552.
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Rana Arslan & Nurcan Bektas. (2010) Antinociceptive effect of methanol extract of Capparis ovata in mice. Pharmaceutical Biology 48:10, pages 1185-1190.
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Jyoti Singh, Dev Nath Singh Gautam, Simant Sourav & Rohit Sharma. (2022) Role of Moringa oleifera Lam. in cancer: Phytochemistry and pharmacological insights . Food Frontiers 4:1, pages 164-206.
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P. Sakuntala, R. Selvaraju & Khaleem Ahmed Jaleeli. (2023) Estimation of essential trace elements in the leaves of some Ocimum and Moringa species plants using Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES) method. Materials Today: Proceedings 92, pages 1129-1132.
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M. Karthik, Ullas Prakash D’Souza, Prasanna Shama Khandige, Vandana Sadananda, S. Gowrish & Savadamoorthi Kamatchi Subramani. (2022) Artocarpus hirsutus Lam Leaf Extract-Evaluation of Analgesic and Anti-Inflammatory Activity. Advances in Pharmacological and Pharmaceutical Sciences 2022, pages 1-9.
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Matheus Cavalcanti de Barros, Ana Gabrielle Barros Silva, Talita Giselly dos Santos Souza, Cristiano Aparecido Chagas, Janaína Carla Barbosa Machado, Magda Rhayanny Assunção Ferreira, Luiz Alberto Lira Soares, Viviane Lansky Xavier, Larissa Cardoso Corrêa de Araújo, Elizabeth Fernanda de Oliveira Borba, Teresinha Gonçalves da Silva, Robson Raion de Vasconcelos Alves, Luana Cassandra Breitenbach Barroso Coelho, Alisson Macário de Oliveira, Thiago Henrique Napoleão & Patrícia Maria Guedes Paiva. (2022) Evaluation of acute toxicity, 28-day repeated dose toxicity, and genotoxicity of Moringa oleifera leaves infusion and powder. Journal of Ethnopharmacology 296, pages 115504.
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Hinal Patel. (2022) IN VITRO TOTAL ANTIOXIDANT CAPACITY AND ANTI-INFLAMMATORY ACTIVITY OF VEGETABLES. INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH, pages 48-49.
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AVNEESH RAWAT, MANJU RAWAT, OM PRAKASH, RAVENDRA KUMAR, HIMANSHU PUNETHA & DHARMENDRA S. RAWAT. (2022) Comparative study on eucalyptol and camphor rich essential oils from rhizomes of Hedychium spicatum Sm. and their pharmacological, antioxidant and antifungal activities. Anais da Academia Brasileira de Ciências 94:3.
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Tanzina Akter, Md Atikur Rahman, Akhi Moni, Md. Aminul Islam Apu, Atqiya Fariha, Md. Abdul Hannan & Md Jamal Uddin. (2021) Prospects for Protective Potential of Moringa oleifera against Kidney Diseases. Plants 10:12, pages 2818.
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Somia Saad, Saida Ouafi, Hassina Meguellati & Nadjette Djemouai. (2021) Chemical diversity analysis and biological activities evaluation of different polyphenolic extracts of Marrubium deserti De Noé from Algeria. Journal of Ethnopharmacology 281, pages 114494.
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Olusegun G. Adebayo, Iheanyichukwu Wopara, Wadioni Aduema, Oloruntoba T. Ebo & Elizabeth B. Umoren. (2021) Long-term consumption of Moringa oleifera -supplemented diet enhanced neurocognition, suppressed oxidative stress, acetylcholinesterase activity and neuronal degeneration in rat’s hippocampus . Drug Metabolism and Personalized Therapy 36:3, pages 223-231.
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Olusegun G. Adebayo, Iheanyichukwu Wopara, Wadioni Aduema, Oloruntoba T. Ebo & Elizabeth B. Umoren. (2021) Long-term consumption of Moringa oleifera -supplemented diet enhanced neurocognition, suppressed oxidative stress, acetylcholinesterase activity and neuronal degeneration in rat’s hippocampus . Drug Metabolism and Personalized Therapy 0:0.
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Navnidhi Chhikara, Amolakdeep Kaur, Sandeep Mann, M.K. Garg, Sajad Ahmad Sofi & Anil Panghal. (2020) Bioactive compounds, associated health benefits and safety considerations of Moringa oleifera L. : an updated review . Nutrition & Food Science 51:2, pages 255-277.
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Faith T. Moichela, Gbenga A. Adefolaju, Ralf R. Henkel & Chinyerum S. Opuwari. (2020) Aqueous leaf extract of Moringa oleifera reduced intracellular ROS production, DNA fragmentation and acrosome reaction in Human spermatozoa in vitro . Andrologia 53:1.
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Ryldene Marques Duarte da Cruz, Renan Marinho Braga, Humberto Hugo Nunes de Andrade, Álefe Brito Monteiro, Isadora Silva Luna, Rayssa Marques Duarte da Cruz, Marcus Tullius Scotti, Francisco Jaime Bezerra Mendonça-Junior & Reinaldo Nóbrega de Almeida. (2020) RMD86, a thiophene derivative, promotes antinociceptive and antipyretic activities in mice. Heliyon 6:11, pages e05520.
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A. Asgari-Kafrani, M. Fazilati & H. Nazem. (2020) Hepatoprotective and antioxidant activity of aerial parts of Moringa oleifera in prevention of non-alcoholic fatty liver disease in Wistar rats. South African Journal of Botany 129, pages 82-90.
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Manas Mathur, Sunita Yadav, Pawan K. Katariya & Raka Kamal. (2014) In vitro propagation and biosynthesis of steroidal sapogenins from various morphogenetic stages of Moringa oleifera Lam., and their antioxidant potential. Acta Physiologiae Plantarum 36:7, pages 1749-1762.
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Mohammad Zafar Imam & Md. Moniruzzaman. (2014) Antinociceptive effect of ethanol extract of leaves of Lannea coromandelica. Journal of Ethnopharmacology 154:1, pages 109-115.
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I. J. Asiedu-Gyekye, S. Frimpong-Manso, C. Awortwe, D. A. Antwi & A. K. Nyarko. (2014) Micro- and Macroelemental Composition and Safety Evaluation of the Nutraceutical Moringa oleifera Leaves . Journal of Toxicology 2014, pages 1-13.
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Xiawei Wei, Xinyi Lv, Qinghe Zhao & Liyan Qiu. (2013) Thermosensitive β-cyclodextrin modified poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) micelles prolong the anti-inflammatory effect of indomethacin following local injection. Acta Biomaterialia 9:6, pages 6953-6963.
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Woranan Kirisattayakul, Jintanaporn Wattanathorn, Terdthai Tong-Un, Supaporn Muchimapura, Panakaporn Wannanon & Jinatta Jittiwat. (2013) Cerebroprotective Effect of Moringa oleifera against Focal Ischemic Stroke Induced by Middle Cerebral Artery Occlusion . Oxidative Medicine and Cellular Longevity 2013, pages 1-10.
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OlufunmilayoE Adejumo, AdelodunL Kolapo & AkintomiwaO Folarin. (2012) Moringa oleifera Lam. (Moringaceae) grown in Nigeria: In vitro antisickling activity on deoxygenated erythrocyte cells. Journal of Pharmacy And Bioallied Sciences 4:2, pages 118.
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S. Mahendran, S. Badami, S. Ravi, B. S. Thippeswamy & V. P. Veerapur. (2011) Antioxidant, analgesic and anti-inflammatory properties of new ninhydrin adduct of embelin. Pharmaceutical Chemistry Journal 45:9, pages 547-551.
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Rana Arslan, Nurcan Bektas & Yusuf Ozturk. (2010) Antinociceptive activity of methanol extract of fruits of Capparis ovata in mice. Journal of Ethnopharmacology 131:1, pages 28-32.
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Bruno Burlando, Luisella Verotta, Laura Cornara & Elisa Bottini-Massa. 2010. Herbal Principles in Cosmetics. Herbal Principles in Cosmetics 41 372 .
Z.A. Zakaria, H. Patahuddin, A.S. Mohamad, D.A. Israf & M.R. Sulaiman. (2010) In vivo anti-nociceptive and anti-inflammatory activities of the aqueous extract of the leaves of Piper sarmentosum. Journal of Ethnopharmacology 128:1, pages 42-48.
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M.R. SulaimanZ.A. Zakaria, A. Abdul Rahman, A.S. Mohamad, M.N. Desa, J. Stanslas, S. Moin & D.A. Israf. (2009) Antinociceptive and Antiedematogenic Activities of Andrographolide Isolated From Andrographis paniculata in Animal Models. Biological Research For Nursing 11:3, pages 293-301.
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