Acanthosis nigricans in the knuckles: An early, accessible, straightforward, and sensitive clinical tool to predict insulin resistance

Gloria González-SaldivarDermatology Division, Department of Medicine, Hospital Universitario “Dr. José E. González”, Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Leon, Mexico

René Rodríguez-GutiérrezEndocrinology Division, Department of Medicine, Hospital Universitario “Dr. José E. González”, Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Leon, Mexico;Knowledge and Evaluation Research Unit, Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America

Andrés Marcelo Treviño-AlvarezEndocrinology Division, Department of Medicine, Hospital Universitario “Dr. José E. González”, Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Leon, Mexico

Minerva Gómez-FloresDermatology Division, Department of Medicine, Hospital Universitario “Dr. José E. González”, Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Leon, Mexico

Juan Montes-VillarrealEndocrinology Division, Department of Medicine, Hospital Universitario “Dr. José E. González”, Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Leon, Mexico

Neri Alejandro Álvarez-VillalobosClinical Research Unit, Hospital Universitario “Dr. José E. González”, Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Leon, Mexico

Anasofía Elizondo-PlazasEndocrinology Division, Department of Medicine, Hospital Universitario “Dr. José E. González”, Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Leon, Mexico

Alejandro Salcido-MontenegroEndocrinology Division, Department of Medicine, Hospital Universitario “Dr. José E. González”, Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Leon, Mexico

Jorge Ocampo-CandianiDermatology Division, Department of Medicine, Hospital Universitario “Dr. José E. González”, Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Leon, Mexico

José Gerardo González-GonzálezEndocrinology Division, Department of Medicine, Hospital Universitario “Dr. José E. González”, Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Leon, MexicoCorrespondence[email protected]

http://orcid.org/0000-0002-6609-9483

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Pappula Vidyasagar, Ashwini Kamble, Praveen Khairkar, Bogum Shravya, Yasmin Sumera, Ashok Rao Matety, Vishwak Reddy, Rakesh Biswas & Ramdas Ransing. (2023) Prevalence, Predictors and Morphological Patterns of Acanthosis Nigricans Between Obese Non-diabetic Patients on Second Generation Antipsychotics Versus Non-obese Insulin Dependent Diabetes mellitus: A Nested Case-Control Study. I.P. Pavlov Russian Medical Biological Herald 31:1, pages 59-68.
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Alexander K.C. Leung, Joseph M. Lam, Benjamin Barankin, Kin Fon Leong & Kam Lun Hon. (2023) Acanthosis Nigricans: An Updated Review. Current Pediatric Reviews 19:1, pages 68-82.
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Andreea-Maria Radu, Mara Carsote, Mihai Cristian Dumitrascu & Florica Sandru. (2022) Acanthosis Nigricans: Pointer of Endocrine Entities. Diagnostics 12:10, pages 2519.
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Neri Alejandro Álvarez‐Villalobos, René Rodríguez‐Gutiérrez, Gloria González‐Saldivar, Adriana Sánchez‐García, Minerva Gómez‐Flores, Carolina Quintanilla‐Sánchez, Andrés Marcelo Treviño‐Álvarez, Leonardo Guadalupe Mancillas‐Adame & José Gerardo González‐González. (2019) Acanthosis nigricans in middle‐age adults: A highly prevalent and specific clinical sign of insulin resistance. International Journal of Clinical Practice 74:3.
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René Rodríguez-Gutiérrez, Manuel E. de la O-Cavazos, Alejandro Salcido-Montenegro, Adriana Sanchez-Garcia, Minerva Gomez-Flores, Victoria Gonzalez-Nava, Dalia Castillo-Gonzalez, Karla M. Santos-Santillana & José Gerardo González-González. (2019) Acanthosis Nigricans in the Knuckles of Infants: A Novel Clinical Marker of High Metabolic Risk. Diabetes Therapy 10:6, pages 2169-2181.
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Ni Lian & Min Chen. (2019) Metabolic Syndrome and Skin Disease: Potential Connection and Risk. International Journal of Dermatology and Venereology 2:2, pages 89-93.
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Acanthosis nigricans in the knuckles: An early, accessible, straightforward, and sensitive clinical tool to predict insulin resistance

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Acanthosis nigricans in the knuckles: An early, accessible, straightforward, and sensitive clinical tool to predict insulin resistance

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