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Drug Evaluations

Trabectedin: an anticancer drug from the sea

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Pages 2735-2743 | Published online: 10 Sep 2009

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Manmeet Kaur, Mandeep Kaur, Tania Bandopadhyay, Aditi Sharma, Anu Priya, Arvind Singh & Bubun Banerjee. (2023) Naturally occurring, natural product inspired and synthetic heterocyclic anti-cancer drugs. Physical Sciences Reviews 8:10, pages 3393-3446.
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Zhichao Tian & Weitao Yao. (2023) Chemotherapeutic drugs for soft tissue sarcomas: a review. Frontiers in Pharmacology 14.
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Lan V. Pham, Elizabeth Pogue & Richard J. Ford. (2018) The Role of Macrophage/B-Cell Interactions in the Pathophysiology of B-Cell Lymphomas. Frontiers in Oncology 8.
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B Englinger, M Mair, W Miklos, C Pirker, T Mohr, S van Schoonhoven, D Lötsch, W Körner, F Ferk, S Knasmüller, P Heffeter, B K Keppler, M Grusch & W Berger. (2017) Loss of CUL4A expression is underlying cisplatin hypersensitivity in colorectal carcinoma cells with acquired trabectedin resistance. British Journal of Cancer 116:4, pages 489-500.
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Mahiru Kawano, Seiji Mabuchi, Toshiko Kishimoto, Takeshi Hisamatsu, Yuri Matsumoto, Tomoyuki Sasano, Ryoko Takahashi, Kenjiro Sawada, Kazuhiro Takahashi, Toshifumi Takahashi, Toshimitsu Hamasaki & Tadashi Kimura. (2014) Combination Treatment With Trabectedin and Irinotecan or Topotecan Has Synergistic Effects Against Ovarian Clear Cell Carcinoma Cells. International Journal of Gynecologic Cancer 24:5, pages 829-837.
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Carmela Pisano, Sabrina Chiara Cecere, Marilena Di Napoli, Carla Cavaliere, Rosa Tambaro, Gaetano Facchini, Cono Scaffa, Simona Losito, Antonio Pizzolorusso & Sandro Pignata. (2013) Clinical Trials with Pegylated Liposomal Doxorubicin in the Treatment of Ovarian Cancer. Journal of Drug Delivery 2013, pages 1-12.
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Yin-Ting Chuang & Chih-Long Chang. (2012) Extending platinum-free interval in partially platinum-sensitive recurrent ovarian cancer by a non-platinum regimen: Its possible clinical significance. Taiwanese Journal of Obstetrics and Gynecology 51:3, pages 336-341.
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Bartomeu Massuti, Manuel Cobo, Carlos Camps, Manuel Dómine, Mariano Provencio, Vicente Alberola, Nuria Viñolas, Rafael Rosell, Miguel Tarón, Vanesa Gutiérrez-Calderón, Pilar Lardelli, Vicente Alfaro, Antonio Nieto & Dolores Isla. (2012) Trabectedin in patients with advanced non-small-cell lung cancer (NSCLC) with XPG and/or ERCC1 overexpression and BRCA1 underexpression and pretreated with platinum. Lung Cancer 76:3, pages 354-361.
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A. Gronchi, B.N. Bui, S. Bonvalot, S. Pilotti, S. Ferrari, P. Hohenberger, R.J. Hohl, G.D. Demetri, A. Le Cesne, P. Lardelli, I. Pérez, A. Nieto, J.C. Tercero, V. Alfaro, E. Tamborini & J.Y. Blay. (2012) Phase II clinical trial of neoadjuvant trabectedin in patients with advanced localized myxoid liposarcoma. Annals of Oncology 23:3, pages 771-776.
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Dale G. Nagle & Yu-Dong Zhou. 2012. Handbook of Marine Natural Products. Handbook of Marine Natural Products 1111 1144 .
Seiji Mabuchi, Takeshi Hisamatsu, Chiaki Kawase, Masami Hayashi, Kenjiro Sawada, Kazuya Mimura, Kazuhiro Takahashi, Toshifumi Takahashi, Hirohisa Kurachi & Tadashi Kimura. (2011) The Activity of Trabectedin As a Single Agent or in Combination with Everolimus for Clear Cell Carcinoma of the Ovary. Clinical Cancer Research 17:13, pages 4462-4473.
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S.B. Kaye, N. Colombo, B.J. Monk, S. Tjulandin, B. Kong, M. Roy, S. Chan, E. Filipczyk-Cisarz, H. Hagberg, I. Vergote, C. Lebedinsky, T. Parekh, P. Santabárbara, Y.C. Park, A. Nieto & A. Poveda. (2011) Trabectedin plus pegylated liposomal doxorubicin in relapsed ovarian cancer delays third-line chemotherapy and prolongs the platinum-free interval. Annals of Oncology 22:1, pages 49-58.
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E.J.O. Soini, B. García San Andrés & T. Joensuu. (2011) Trabectedin in the treatment of metastatic soft tissue sarcoma: cost-effectiveness, cost-utility and value of information. Annals of Oncology 22:1, pages 215-223.
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