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Expert Opinion on Drug Metabolism & Toxicology Volume 4, 2008 - Issue 11
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Review

Biomarkers in oncology drug development: rescuers or troublemakers?

Estelle Marrer Novartis Institutes for BioMedical Research, Translational Sciences, Novartis, Klybeckstr. 141, CH-4002 Basel, Switzerland +41 616962095; +41 616966212; [email protected]
&
Frank Dieterle Novartis Institutes for BioMedical Research, Translational Sciences, Novartis, Klybeckstr. 141, CH-4002 Basel, Switzerland +41 616962095; +41 616966212; [email protected]
Pages 1391-1402 | Published online: 25 Oct 2008

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Patrick Y Muller & Frank Dieterle. (2009) Tissue-specific, non-invasive toxicity biomarkers: translation from preclinical safety assessment to clinical safety monitoring. Expert Opinion on Drug Metabolism & Toxicology 5:9, pages 1023-1038.
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Articles from other publishers (13)

Paulina Krzyszczyk, Alison Acevedo, Erika J. Davidoff, Lauren M. Timmins, Ileana Marrero-Berrios, Misaal Patel, Corina White, Christopher Lowe, Joseph J. Sherba, Clara Hartmanshenn, Kate M. O’Neill, Max L. Balter, Zachary R. Fritz, Ioannis P. Androulakis, Rene S. Schloss & Martin L. Yarmush. (2019) The growing role of precision and personalized medicine for cancer treatment. TECHNOLOGY 06:03n04, pages 79-100.
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H.H. Oh, S. Surapaneni & J.Y. Hui. 2017. A Comprehensive Guide to Toxicology in Nonclinical Drug Development. A Comprehensive Guide to Toxicology in Nonclinical Drug Development 685 707 .
Adam Falconi, Gilberto Lopes & Jayson L. Parker. (2014) Biomarkers and Receptor Targeted Therapies Reduce Clinical Trial Risk in Non?Small-Cell Lung Cancer. Journal of Thoracic Oncology 9:2, pages 163-169.
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Hyesun H. Oh, Sekhar Surapaneni & Julia Y. Hui. 2013. A Comprehensive Guide to Toxicology in Preclinical Drug Development. A Comprehensive Guide to Toxicology in Preclinical Drug Development 543 565 .
Uwe Christians, Volker Schmitz, Jost Klawitter & Jelena Klawitter. 2012. Analytical Techniques for Clinical Chemistry. Analytical Techniques for Clinical Chemistry 691 774 .
Michael Forstner. (2012) Benefit–risk management in the age of personalized healthcare. Personalized Medicine 9:5, pages 507-514.
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Lynne Dobson, Catherine Conway, Alan Hanley, Alex Johnson, Sean Costello, Anthony O’Grady, Yvonne Connolly, Hilary Magee, Daniel O’Shea, Michael Jeffers & Elaine Kay. (2010) Image analysis as an adjunct to manual HER-2 immunohistochemical review: a diagnostic tool to standardize interpretation. Histopathology 57:1, pages 27-38.
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Jeban Ganesalingam & Robert Bowser. (2010) The application of biomarkers in clinical trials for motor neuron disease. Biomarkers in Medicine 4:2, pages 281-297.
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Lixia Yao, James A. Evans & Andrey Rzhetsky. (2010) Novel opportunities for computational biology and sociology in drug discovery. Trends in Biotechnology 28:4, pages 161-170.
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Emma Dean, Loaie El-Helw & Jurjees Hasan. (2010) Targeted Therapies in Epithelial Ovarian Cancer. Cancers 2:1, pages 88-113.
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Andrea B Apolo, Matthew Milowsky & Dean F Bajorin. (2009) Clinical states model for biomarkers in bladder cancer. Future Oncology 5:7, pages 977-992.
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Lixia Yao, James A. Evans & Andrey Rzhetsky. (2009) Novel opportunities for computational biology and sociology in drug discovery. Trends in Biotechnology 27:9, pages 531-540.
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Julio E. Celis, Teresa Cabezón, José M.A. Moreira, Pavel Gromov, Irina Gromova, Vera Timmermans-Wielenga, Takuji Iwase, Futoshi Akiyama, Naoko Honma & Fritz Rank. (2009) Molecular characterization of apocrine carcinoma of the breast: Validation of an apocrine protein signature in a well‐defined cohort. Molecular Oncology 3:3, pages 220-237.
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