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Expert Review of Anti-infective Therapy Volume 1, 2003 - Issue 2
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Review

Natural products and synthetic compounds as immunomodulators

Oliver Kayser Freie Universität Berlin, Institute of Pharmacy – Pharmaceutical Technology, Biopharmacy and Biotechnology, Kelchstrasse 31, D-12169 Berlin, Germany. [email protected]
,
K Noël Masihi Robert Koch-Institut, Department of Infectious Diseases, Viral Infections Unit, Nordufer 20, D-13353 Berlin, Germany
&
Albrecht F Kiderlen Robert Koch-Institut, Department of Infectious Diseases, Cellular Defense Mechanisms Unit, Nordufer 20, D-13353 Berlin, Germany
Pages 319-335 | Published online: 10 Jan 2014

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Yungui Bai, Pengying Zhang, Guochuang Chen, Jianfeng Cao, Taotao Huang & Kaoshan Chen. (2012) Macrophage immunomodulatory activity of extracellular polysaccharide (PEP) of Antarctic bacterium Pseudoaltermonas sp.S-5. International Immunopharmacology 12:4, pages 611-617.
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K. Noel Masihi. 2011. Principles of Immunopharmacology. Principles of Immunopharmacology 411 435 .
Amin F. Majdalawieh & Ronald I. Carr. (2010) In Vitro Investigation of the Potential Immunomodulatory and Anti-Cancer Activities of Black Pepper ( Piper nigrum ) and Cardamom ( Elettaria cardamomum ) . Journal of Medicinal Food 13:2, pages 371-381.
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M. P. Fernandes, N. M. Inada, M. R. Chiaratti, F. F. B. Araújo, F. V. Meirelles, M. T. S. Correia, L. C. B. B. Coelho, M. J. M. Alves, F. R. Gadelha & A. E. Vercesi. (2010) Mechanism of Trypanosoma cruzi death induced by Cratylia mollis seed lectin. Journal of Bioenergetics and Biomembranes 42:1, pages 69-78.
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Igor A. Schepetkin, Liliya N. Kirpotina, Larissa Jakiw, Andrei I. Khlebnikov, Christie L. Blaskovich, Mark A. Jutila & Mark T. Quinn. (2009) Immunomodulatory Activity of Oenothein B Isolated from Epilobium angustifolium . The Journal of Immunology 183:10, pages 6754-6766.
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T. Brendler & B.-E. van Wyk. (2008) A historical, scientific and commercial perspective on the medicinal use of Pelargonium sidoides (Geraniaceae). Journal of Ethnopharmacology 119:3, pages 420-433.
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Igor A. Schepetkin, Gang Xie, Liliya N. Kirpotina, Robyn A. Klein, Mark A. Jutila & Mark T. Quinn. (2008) Macrophage immunomodulatory activity of polysaccharides isolated from Opuntia polyacantha. International Immunopharmacology 8:10, pages 1455-1466.
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Xiaoming Chen, Jianxin Lu, Yangde Zhang, Jiantai He, Xunzhi Guo, Gengyuan Tian & Liqin Jin. (2008) Studies of macrophage immuno-modulating activity of polysaccharides isolated from Paecilomyces tenuipes. International Journal of Biological Macromolecules 43:3, pages 252-256.
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Anwei Cheng, Fachun Wan, Jiaqi Wang, Zhengyu Jin & Xueming Xu. (2008) Macrophage immunomodulatory activity of polysaccharides isolated from Glycyrrhiza uralensis fish. International Immunopharmacology 8:1, pages 43-50.
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A. Belicová, L. Križková, J. Krajčovič, D. Jurkovič, M. Sojka, L. Ebringer & R. Dušinský. (2007) Antimicrobial susceptibility ofEnterococcus species isolated from slovak bryndza cheese. Folia Microbiologica 52:2.
Crossref
Igor A. Schepetkin, Craig L. Faulkner, Laura K. Nelson-Overton, James A. Wiley & Mark T. Quinn. (2005) Macrophage immunomodulatory activity of polysaccharides isolated from Juniperus scopolorum. International Immunopharmacology 5:13-14, pages 1783-1799.
Crossref

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