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Abstract
Herein, we report the use of whole cells of Brazilian marine-derived fungi in the biotransformation and biodegradation of organic compounds, particularly, Knoevenagel adducts. A preliminary screening with five marine-derived fungi revealed that these microorganisms promoted the bioreduction and biodegradation of four Knoevenagel adducts. Additionally, a biotransformation pathway for these compounds was proposed, which suggested the presence of ene-reductase and alcohol dehydrogenase in the marine-derived fungi, which catalysed the microbial transformation of the substrates. In summary, the fast biodegradation of organic molecules has an ecological relevance since several of these compounds and their biotransformed products have aquatic environment impact.
Acknowledgements
The authors thank all the support of the Chemical Analysis Center (Institute of Chemistry of São Carlos, University of São Paulo) for the NMR and FTIR analyses.
Ethical approval
The authors declare that they have no conflict of interest.
Author contributions
Lucas Lima Zanin: designed and performed the experiments; developed the manuscript. Thayane Melo de Queiroz: designed and performed the experiments; developed the manuscript. André Luiz Meleiro Porto: guided the research and revised the manuscript; funding support.
Disclosure statement
No potential conflict of interest was reported by the author(s).