Accuracy of Essential TNM to stage large colorectal (T3/T4) cancers in absence of nodal status information

Figures & data

Figure 1. Essential TNM Flowchart for colorectal cancer staging [4].

Table 1. TNM Regional nodes status (N) in cases of advanced (T3/T4) colorectal cancer from selected cancer registries in different countries.

	Regional nodes
Tumour size	N0		N+		NX
	n	%	N	%	n	%	Total
Africa
T3	38	43.7	39	44.8	10	11.5	87
T4	24	33.3	32	44.4	16	22.2	72
T3 + T4	62		71		26	16.4	159
N+^a (%)			53.4
Latin America
T3	1337	45.1	1419	47.8	210	7.1	2966
T4	500	37.6	710	53.3	121	9.1	1331
T3 + T4	1837		2129		331	7.7	4297
N+^a (%)			53.7
USA
T3	44,640	49.9	44,281	49.5	510	0.6	89,431
T4	11,459	35.8	19,698	61.5	872	2.7	32,029
T3 + T4	56,099		63,979		1382	1.1	121,460
N+^a (%)			53.3
TOTAL
T3	46,015	49.8	45,739	49.5	730	0.8	92,484
T4	11,983	35.8	20,440	61.1	1009	3.0	33,432
T3 + T4	57,998		66,179		1739	1.4	125,916
N+ ^a (%)			53.3

^aN+ amongst T3/T4 with N information N (N0,N+).

Brierley J, Gospodarowicz M, Wittekind C. TNM classification of malignant tumours. 8th ed. Oxford UK: Wiley Blackwell; 2017.

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Data availability statement

Disaggregated data on large colorectal cancers (T3/T4) from the individual cancer registries that contributed for Africa (via the AFCRN) and for Latin America to this study are available in Supplementary Appendix Table 1. Co-authors affiliated to the individual participating registries in this study can be contacted for the data.