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Journal of Dermatological Treatment Volume 35, 2024 - Issue 1
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Case Report

Oral abrocitinib in the treatment of granuloma annulare: a case report

Wenyan Liua Institute of Dermatology, Guangzhou Medical University, Guangzhou, P.R. China;b Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou, P.R. ChinaView further author information
,
Weifeng Chena Institute of Dermatology, Guangzhou Medical University, Guangzhou, P.R. China;b Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou, P.R. ChinaView further author information
,
Xin Tiana Institute of Dermatology, Guangzhou Medical University, Guangzhou, P.R. China;b Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou, P.R. ChinaView further author information
,
Yihui Yua Institute of Dermatology, Guangzhou Medical University, Guangzhou, P.R. China;b Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou, P.R. ChinaView further author information
,
Junhui Zhua Institute of Dermatology, Guangzhou Medical University, Guangzhou, P.R. China;b Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou, P.R. ChinaView further author information
,
Jingyao Lianga Institute of Dermatology, Guangzhou Medical University, Guangzhou, P.R. China;b Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou, P.R. ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-9635-9162View further author information
ORCID Icon &
Xibao Zhanga Institute of Dermatology, Guangzhou Medical University, Guangzhou, P.R. China;b Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou, P.R. ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-1893-4779View further author information
ORCID Icon show all
Article: 2313090 | Received 07 Nov 2023, Accepted 28 Jan 2024, Published online: 05 Feb 2024

Figures & data

Figure 1. A 29-year-old female presented with annular erythema with mild annular induration on the left lower extremity before abrocitinib treatment (A), and progressive thinning of the plaques two, four weeks after abrocitinib treatment (B, C) and near complete clearance of lesions following six weeks of abrocitinib treatment (D).

Figure 1. A 29-year-old female presented with annular erythema with mild annular induration on the left lower extremity before abrocitinib treatment (A), and progressive thinning of the plaques two, four weeks after abrocitinib treatment (B, C) and near complete clearance of lesions following six weeks of abrocitinib treatment (D).

Figure 2. A skin biopsy showed hyperkeratosis, hickening of the epidermis, and a palisaded arrangement of epithelioid granulomas, with collagen egeneration (A, 20×; B, 40×).

Figure 2. A skin biopsy showed hyperkeratosis, hickening of the epidermis, and a palisaded arrangement of epithelioid granulomas, with collagen egeneration (A, 20×; B, 40×).

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