543
Views
0
CrossRef citations to date
0
Altmetric
Case Report

A case of generalized eosinophilic pustular folliculitis: treatment with JAK inhibitor

, , &
Article: 2331785 | Received 02 Jan 2024, Accepted 27 Feb 2024, Published online: 26 Mar 2024

Figures & data

Figure 1. (a,c) Clinical manifestation before treatment with tofacitinib. Multiple papules and macules on forechest and left lower limb, with most of them breaking and crusting at the top. (b,d) Clinical manifestation after treatment with upacitinib. The papules have almost faded, leaving significant hyperpigmentation.

Figure 1. (a,c) Clinical manifestation before treatment with tofacitinib. Multiple papules and macules on forechest and left lower limb, with most of them breaking and crusting at the top. (b,d) Clinical manifestation after treatment with upacitinib. The papules have almost faded, leaving significant hyperpigmentation.

Figure 2. (a,c,d) Histopathology manifestation of the lesion obtained from the left upper arm. Hyperkeratosis, focal parakeratosis, and acanthosis. Follicular epithelium spongiosis and eosinophil infiltration were observed. Perivascular infiltrated by eosinophil and lymphocyte mildly in superficial and middle dermis (hematoxylineosin, scale bars: (a) 200×, (c) 40×, and (d) 200×). (b) Serum levels of eosinophil markers during the treatment course.

Figure 2. (a,c,d) Histopathology manifestation of the lesion obtained from the left upper arm. Hyperkeratosis, focal parakeratosis, and acanthosis. Follicular epithelium spongiosis and eosinophil infiltration were observed. Perivascular infiltrated by eosinophil and lymphocyte mildly in superficial and middle dermis (hematoxylineosin, scale bars: (a) 200×, (c) 40×, and (d) 200×). (b) Serum levels of eosinophil markers during the treatment course.

Data availability statement

All data generated or used during the case appear in the submitted manuscription.