Aquaporin 1, Aquaporin 3 and Aquaporin 5 expression and EGFR mutation in malignant pleural mesotheliomas: an imunohistochemical and molecular study

Figures & data

Table 1. Clinical and prognostic features of the patients and results from the EGFR mutation analysis and immunohistochemical staining.

Variable	Categories	Total
Sex	Male	40
	Female	20
Age	<60	29
	≥60	31
Histology	Epithelioid	50
	Sarcomatoid	6
	Biphasic	4
Stage	1	0
	2	3
	3	13
	4	44
Survival time (months)	0–5	16
	6–10	20
	11–20	11
	>20	13
EGFR mutation	−	60
	+	0
AQP1	Negative	1
	Weak	1
	Moderate	8
	Strong	50
AQP3	Negative	22
	Weak	7
	Moderate	26
	Strong	5
AQP5	Negative	37
	Weak	11
	Moderate	12
	Strong	0

Figure 1. Diffuse (extensity score = 4) and strong (intensity score = 3) expression of AQP1 in MPM (AQP1 200×).

Figure 2. Focal (extensity score = 2) and moderate (intensity score = 2) expression of AQP3 in MPM (AQP3, 200×).

Figure 3. Focal (extensity score = 1) and weak (intensity score = 1) expression of AQP5 in MPM (AQP5, 200×).