Antiproliferative potential of methanolic and aqueous extracts and their methanolic fractions derived from fruits of Bersama engleriana against a panel of four cancer cell lines

Michèle Stella Majoumouo1 Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plant Studies, Department of Biochemistry, University of Yaoundé, P.O. Box 812, Yaoundé, Cameroon;2 Cancer Biology and Inﬂammatory Disorder Division, Council of Scientiﬁc and Industrial Research-Indian Institute of Chemical Biology, 4 Raja S.C. Mallick Road, Kolkata, West Bengal700032, India;3 Department of Biotechnology, University of the Western Cape, Private Bag X17, Bellville7535, South AfricaView further author information

Marius Belmondo Tincho3 Department of Biotechnology, University of the Western Cape, Private Bag X17, Bellville7535, South Africa;4 Division of Medical Virology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, 7925, South AfricaCorrespondence[email protected]
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Thureyah Morris5 Food Toxicology Laboratory, Department of Medical Bioscience, University of the Western Cape, Private Bag X17, Bellville7535, South AfricaView further author information

Donavon Charles Hiss5 Food Toxicology Laboratory, Department of Medical Bioscience, University of the Western Cape, Private Bag X17, Bellville7535, South AfricaView further author information

Fabrice Fekam Boyom1 Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plant Studies, Department of Biochemistry, University of Yaoundé, P.O. Box 812, Yaoundé, CameroonView further author information

Chitra Mandal2 Cancer Biology and Inﬂammatory Disorder Division, Council of Scientiﬁc and Industrial Research-Indian Institute of Chemical Biology, 4 Raja S.C. Mallick Road, Kolkata, West Bengal700032, IndiaView further author information

Tianzhu Zang6 Systems Pharmacology & Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, USAView further author information

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Antiproliferative potential of methanolic and aqueous extracts and their methanolic fractions derived from fruits of Bersama engleriana against a panel of four cancer cell lines

Table 1. Yields of aqueous and methanol extracts and fractions obtained from the active extract of Bersama engleriana

Table 2. Phytochemical screening of aqueous and methanolic extracts from Bersama engleriana

Table 3. Effect of crude extracts and fractions from fruits of Bersama engleriana on drug-resistant A549 human lung carcinoma epithelial cells

Table 4. Cytotoxic effects of selected fractions against U-87MG, MG-63, MIA-PaCa2 and A549 cancer cell lines, and the cytotoxic effects of F3 against HFF cells and their selectivity index for F3

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Antiproliferative potential of methanolic and aqueous extracts and their methanolic fractions derived from fruits of Bersama engleriana against a panel of four cancer cell lines

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Table 1. Yields of aqueous and methanol extracts and fractions obtained from the active extract of Bersama engleriana

Table 2. Phytochemical screening of aqueous and methanolic extracts from Bersama engleriana

Table 3. Effect of crude extracts and fractions from fruits of Bersama engleriana on drug-resistant A549 human lung carcinoma epithelial cells

Table 4. Cytotoxic effects of selected fractions against U-87MG, MG-63, MIA-PaCa2 and A549 cancer cell lines, and the cytotoxic effects of F3 against HFF cells and their selectivity index for F3

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