Marchiafava-Bignami disease as a cause of toxic leukoencephalopathy in a 27-year-old patient: a case report

Figures & data

Figure 1. T2W FLAIR, DWI, and ADC sequences, respectively. Abnormal T2 hyperintensity and diffusion restriction involving the bilateral cerebral white matter, including the corona radiata and the centrum semiovale of the frontoparietal lobes.

Figure 2. T2W FLAIR, DWI, and ADC sequences, respectively. Abnormal T2 hyperintensity and diffusion restriction involving the splenium of the corpus callosum.

Table 1. Serum thiamine, folate, and B12 concentrations.

Laboratory study	Result	Reference range
Thiamine (Vitamin B1)	<6 nmol/L	8–30 nmol/L
Folate (Vitamin B9)	9.9 ng/mL	≥7.8 ng/mL
Cobalamin (Vitamin B12)	864.0 pg/mL	180.0-914.0 pg/mL

Data availability statement

No additional data for this case report are available for sharing in order to protect patient privacy.