Emerging perspectives on laminopathies

Figures & data

Table 1 Laminopathies and related genes

Gene	Protein	Disease
LMNA	Lamin A/C	AD-EDMD, LGMD1B, MDCL, DCM, HGPS, a-wS, MAD, AR-CMT2A
LMNBI	Lamin B receptor	AD leukodystrophy
STA/EMD	Emerin	XL-EDMD
SYNEI	Nesprin 1	EDMD-like, cerebellar ataxia
SYNE2	Nesprin 2	EDMD-like
TMEM43	LUMA	EDMD-like
TMPO	LAP2α	DCM
TORIA	Torsin A	Dystonia
TORIAIPI	LAP1B	Myopathy with contractures, cardiomyopathy

Abbreviations: AD, autosomal-dominant; a-WS, atypical Werner syndrome; EDMD, Emery–Dreifuss muscular dystrophy; LGMD, limb-girdle muscular dystrophy; MDCL, muscular dystrophy, congenital, LMNA-related; DCM, dilated cardiomyopathy; HGPS, Hutchinson–Gilford progeria syndrome; MAD, mandibuloacral dysplasia; AR, autosomal-recessive; CMT, Charcot–Marie–Tooth; XL, X-linked.