1,585
Views
23
CrossRef citations to date
0
Altmetric
Original Article

Anti-amnesic effect of Ficus religiosa in scopolamine-induced anterograde and retrograde amnesia

, , &
Pages 234-240 | Received 09 Mar 2009, Accepted 29 Jul 2009, Published online: 25 Jan 2010

Figures & data

Figure 1. Treatment schedule and division of groups for elevated plus-maze paradigm. m, minutes; TL, transfer latency; h, hours; SCO, scopolamine (1 mg/kg, i.p.); FRFE 10, 50, and 100, Ficus religiosa fig extract (10, 50, and 100 mg/kg, i.p.); CYP, cyproheptadine (4 mg/kg, i.p.).

Figure 1.  Treatment schedule and division of groups for elevated plus-maze paradigm. m, minutes; TL, transfer latency; h, hours; SCO, scopolamine (1 mg/kg, i.p.); FRFE 10, 50, and 100, Ficus religiosa fig extract (10, 50, and 100 mg/kg, i.p.); CYP, cyproheptadine (4 mg/kg, i.p.).

Figure 2. Treatment schedule and division of groups for modified passive avoidance paradigm. m, minutes; SDL, step down latency; NT, number of trials; NM, number of mistakes; h, hours; SCO, scopolamine (1 mg/kg, i.p.); FRFE 10, 50, and 100, Ficus religiosa fig extract (10, 50, and 100 mg/kg, i.p.); CYP, cyproheptadine (4 mg/kg, i.p.).

Figure 2.  Treatment schedule and division of groups for modified passive avoidance paradigm. m, minutes; SDL, step down latency; NT, number of trials; NM, number of mistakes; h, hours; SCO, scopolamine (1 mg/kg, i.p.); FRFE 10, 50, and 100, Ficus religiosa fig extract (10, 50, and 100 mg/kg, i.p.); CYP, cyproheptadine (4 mg/kg, i.p.).

Figure 3. Effect of FRFE on transfer latency in scopolamine-induced amnesia (before learning). a,a*p < 0.05 as compared to Group I (naive) 1st and 2nd day respectively; b,b*p < 0.05 as compared to Group II (vehicle control) 1st and 2nd day respectively, and c,c*p < 0.05 as compared to Group V (FRFE 100 mg/kg) 1st and 2nd day respectively.

Figure 3.  Effect of FRFE on transfer latency in scopolamine-induced amnesia (before learning). a,a*p < 0.05 as compared to Group I (naive) 1st and 2nd day respectively; b,b*p < 0.05 as compared to Group II (vehicle control) 1st and 2nd day respectively, and c,c*p < 0.05 as compared to Group V (FRFE 100 mg/kg) 1st and 2nd day respectively.

Figure 4. Effect of FRFE on transfer latency in scopolamine-induced amnesia (before retrieval). ap < 0.05 as compared to Group VIII (naive), bp < 0.05 as compared to Group IX (vehicle control), and cp < 0.05 as compared to Group XII (FRFE 100 mg/kg).

Figure 4.  Effect of FRFE on transfer latency in scopolamine-induced amnesia (before retrieval). ap < 0.05 as compared to Group VIII (naive), bp < 0.05 as compared to Group IX (vehicle control), and cp < 0.05 as compared to Group XII (FRFE 100 mg/kg).

Figure 5. Effect of FRFE on number of trials and mistakes in scopolamine-induced amnesia (before learning). a,a*p < 0.05 as compared to Group XV (naive) 1st and 2nd day respectively, b,b*p < 0.05 as compared to Group XVI (vehicle control) 1st and 2nd day respectively, and c,c*p < 0.05 as compared to Group XIX (FRFE 100 mg/kg) 1st and 2nd day respectively.

Figure 5.  Effect of FRFE on number of trials and mistakes in scopolamine-induced amnesia (before learning). a,a*p < 0.05 as compared to Group XV (naive) 1st and 2nd day respectively, b,b*p < 0.05 as compared to Group XVI (vehicle control) 1st and 2nd day respectively, and c,c*p < 0.05 as compared to Group XIX (FRFE 100 mg/kg) 1st and 2nd day respectively.

Figure 6. Effect of FRFE on step down latency in scopolamine-induced amnesia (before retrieval). ap < 0.05 as compared to Group XXII (naive), bp < 0.05 as compared to Group XXIII (vehicle control), and cp < 0.05 as compared to Group XXVI (FRFE 100 mg/kg).

Figure 6.  Effect of FRFE on step down latency in scopolamine-induced amnesia (before retrieval). ap < 0.05 as compared to Group XXII (naive), bp < 0.05 as compared to Group XXIII (vehicle control), and cp < 0.05 as compared to Group XXVI (FRFE 100 mg/kg).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.