Two natural compounds – a benzofuran and a phenylpropane – from Artemisia dracunculus

Abstract

The structure elucidation of three metabolites herniarin (7-methoxy-2H-chromen-2-one, 1), phytoalexin (5-acetyl-6-hydroxy-2-(1-hydroxy-1-methylethyl)benzofuran, 2), and prestragol (3-(4′-methoxyphenyl)-prop-1,2-diol, 3) isolated from Artemisia dracunculus was determined on the basis of 1D, 2D NMR methods and by an X-ray crystallographic determination.

Keywords:

• Artemisia dracunculus
• Asteraceae
• herniarin
• prestragol
• phytoalexin

Acknowledgments

We are grateful to Dr M. Gelbke for his helpful assistance for the NMR spectra interpretation, to Mr C. Moulard and to Dr M. Luhmer for measurements of MS and NMR spectra, to the “Department of International Relations” of ULB (Belgium), UH2C, and the “CNRST” of Morocco for their financial support.