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Computational and Mathematical Methods in Medicine
An Interdisciplinary Journal of Mathematical, Theoretical and Clinical Aspects of Medicine
Volume 11, 2010 - Issue 4
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Original Articles

A classification system for hospital-based infection outbreaks

, &
Pages 297-311 | Received 16 Feb 2009, Accepted 21 Jan 2010, Published online: 30 Sep 2010
 

Abstract

Outbreaks of infection within semi-closed environments such as hospitals, whether inherent in the environment (such as Clostridium difficile (C.Diff) or Methicillin-resistant Staphylococcus aureus (MRSA) or imported from the wider community (such as Norwalk-like viruses (NLVs)), are difficult to manage. As part of our work on modelling such outbreaks, we have developed a classification system to describe the impact of a particular outbreak upon an organization. This classification system may then be used in comparing appropriate computer models to real outbreaks, as well as in comparing different real outbreaks in, for example, the comparison of differing management and containment techniques and strategies. Data from NLV outbreaks in the Hull and East Yorkshire Hospitals NHS Trust (the Trust) over several previous years are analysed and classified, both for infection within staff (where the end of infection date may not be known) and within patients (where it generally is known). A classification system consisting of seven elements is described, along with a goodness-of-fit method for comparing a new classification to previously known ones, for use in evaluating a simulation against history and thereby determining how ‘realistic’ (or otherwise) it is.

Notes

Additional information

Notes on contributors

Maurice Madeo

1 1. [email protected]

Roger Phillips

2 2. [email protected]

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