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Expert Opinion on Pharmacotherapy Volume 10, 2009 - Issue 16
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Drug Evaluations

Vildagliptin in clinical practice: a review of literature

Moulinath Banerjee Central Manchester University Hospitals Foundation Trust, Department of Medicine, Manchester, M13 9WL, UK +44 0 161 276 4443 or 0044 161 276 4066; +44 0 161 276 3630; [email protected]
,
Naveed Younis University Hospitals South Manchester Foundation Trust, Department of Diabetes and Endocrinology, Manchester, UK
&
Handrean Soran Central Manchester University Hospitals Foundation Trust, Department of Medicine, Manchester, M13 9WL, UK +44 0 161 276 4443 or 0044 161 276 4066; +44 0 161 276 3630; [email protected]
Pages 2745-2757 | Published online: 30 Oct 2009
 
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Abstract

Vildagliptin is the second member of the DPP-IV inhibitor class of drugs licensed for the treatment of type 2 diabetes mellitus (T2DM). The novel action of these drugs has promoted a new outlook in the pathobiology of T2DM. This review undertakes to examine the clinical studies published to date, with the aim of evaluating the position of vildagliptin among the drugs that are now available to treat this common dysmetabolic state.

Acknowledgements

Support from the NIHR Manchester Biomedical Research Centre is acknowledged.

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