Study on the acute toxicity of sodium taurocholate via zebrafish mortality, behavioral response, and NMR-metabolomics analysis

References

• Abdallah, S.J., Thomas, B.S., and Jonz, M.G., 2015. Aquatic surface respiration and swimming behaviour in adult and developing zebrafish exposed to hypoxia. The Journal of Experimental Biology, 218 (Pt 11), 1777–1786.
   PubMed Web of Science ®Google Scholar
• Attili, A.F., et al., 1986. Bile acid-induced liver toxicity: relation to the hydrophobic-hydrophilic balance of bile acids. Medical Hypotheses, 19 (1), 57–69.
   PubMed Web of Science ®Google Scholar
• Bartrons, R., and Caro, J., 2007. Hypoxia, glucose metabolism and the Warburg’s effect. Journal of Bioenergetics and Biomembranes, 39 (3), 223–229.
   PubMed Web of Science ®Google Scholar
• Begley, M., Hill, C., and Gahan, C.G.M., 2006. Bile salt hydrolase activity in probiotics. Applied and Environmental Microbiology, 72 (3), 1729–1738.
   PubMed Web of Science ®Google Scholar
• Benedetti, A., et al., 1997. Cytotoxicity of bile salts against biliary epithelium: a study in isolated bile ductule fragments and isolated perfused rat liver. Hepatology, 26 (1), 9–21.
   PubMed Web of Science ®Google Scholar
• Bergmini, A., et al., 1997. Bile acids with differing hydrophilic-hydrophobic properties do not influence cytokine production by human monocytes and murine Kupffer cells. Hepatology, 25 (4), 927–933.
   PubMed Web of Science ®Google Scholar
• Billington, D., et al., 1980. Effects of bile salts on the plasma membranes of isolated rat hepatocytes. The Biochemical Journal, 188 (2), 321–327.
   PubMed Web of Science ®Google Scholar
• Brisson, D., et al., 2001. Glycerol: A neglected variable in metabolic processes? BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology, 23 (6), 534–542.
   PubMed Web of Science ®Google Scholar
• Bustamam, M.S.A., et al., 2022. The immunostimulant effects of Isochrysis galbana supplemented diet on the spleen of red hybrid tilapia (Oreochromis spp.) evaluated by nuclear magnetic resonance metabolomics. Aquaculture Nutrition, 2022, 1–22.
   Web of Science ®Google Scholar
• Cachat, J., et al., 2010. Measuring behavioral and endocrine responses to novelty stress in adult zebrafish. Nature Protocols, 5 (11), 1786–1799.
   PubMed Web of Science ®Google Scholar
• Chávez-talavera, O., et al., 2017. Bile acid control of metabolism and inflammation in obesity, type 2 diabetes, dyslipidemia and NAFLD. Gastroenterology, 152 (7), 1679–1694.e3. Iss
   PubMed Web of Science ®Google Scholar
• Dantzer, R., 2009. Cytokine, sickness behavior, and depression. Immunology and Allergy Clinics of North America, 29 (2), 247–264.
   PubMed Web of Science ®Google Scholar
• Desmoulin, F., et al., 2013. Metabonomics analysis of plasma reveals the lactate to cholesterol ratio as an independent prognostic factor of short-term mortality in acute heart failure. PLoS One, 8 (4), e60737.
   PubMed Web of Science ®Google Scholar
• De Smet, I., et al., 1995. Significance of bile salt hydrolytic activities of lactobacilliIsochrysis galbanaOreochromis. The Journal of Applied Bacteriology, 79 (3), 292–301.
   PubMedGoogle Scholar
• Fickert, P., et al., 2005. Oncosis represents the main type of cell death in mouse models of cholestasis. Journal of Hepatology, 42 (3), 378–385.
   PubMed Web of Science ®Google Scholar
• Fulcher, N., et al., 2017. Neurochemical and behavioral responses to unpredictable chronic mild stress following developmental isolation: the zebrafish as a model for major depression. Zebrafish, 14 (1), 23–34.
   PubMed Web of Science ®Google Scholar
• Gaifem, J., et al., 2018. L-threonine supplementation during colitis onset delays disease recovery. Frontiers in Physiology, 9 (SEP), 1247.
   PubMedGoogle Scholar
• Ganeshan, K., and Chawla, A., 2014. Metabolic regulation of immune responses. Annual Review of Immunology, 32, 609–634.
   PubMed Web of Science ®Google Scholar
• Gibney, S.M., and Drexhage, H.A., 2013. Evidence for a dysregulated immune system in the etiology of psychiatric disorders. Journal of Neuroimmune Pharmacology, 8 (4), 900–920.
   PubMed Web of Science ®Google Scholar
• Gopal-Srivastava, R., and Hylemon, P.B., 1988. Purification and characterization of bile salt hydrolase from Clostridium perfringens. Journal of Lipid Research, 29 (8), 1079–1085. https://doi.org/10.1016/s0022-2275(20)38464-9
   PubMed Web of Science ®Google Scholar
• González-Regueiro, J.A., et al., 2017. The role of bile acids in glucose metabolism and their relation with diabetes. Annals of Hepatology, 16 (Suppl. 1), S16–S20.
   PubMed Web of Science ®Google Scholar
• Gray, L.R., Tompkins, S.C., and Taylor, E.B., 2014. Regulation of pyruvate metabolism and human disease. Cellular and Molecular Life Sciences, 71 (14), 2577–2604.
   PubMed Web of Science ®Google Scholar
• Habte-Tsion, H.M., et al., 2015. A deficiency or an excess of dietary threonine level affects weight gain, enzyme activity, immune response and immune-related gene expression in juvenile blunt snout bream (Megalobrama amblycephala). Fish & Shellfish Immunology, 42 (2), 439–446.
   PubMed Web of Science ®Google Scholar
• Haddad, J.J., 2003. Science review: redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: role for hypoxia-inducible factor-1α. Critical Care, 7 (1), 47–54.
   PubMed Web of Science ®Google Scholar
• Hatoum, O.A., and Binion, D.G., 2005. The vasculature and inflammatory bowel disease: contribution to pathogenesis and clinical pathology. Inflammatory Bowel Diseases, 11 (3), 304–313.
   PubMed Web of Science ®Google Scholar
• He, G., et al., 2014. The effect of HIF-1α on glucose metabolism, growth and apoptosis of pancreatic cancerous cells. Asia Pacific Journal of Clinical Nutrition, 23 (1), 174–180.
   PubMed Web of Science ®Google Scholar
• Hill, D.A., et al., 2012. Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation. Nature Medicine, 18 (4), 538–546.
   PubMed Web of Science ®Google Scholar
• Hofmann, A.F., 2002. Cholestatic liver disease: pathophysiology and therapeutic options. Liver, 22 (Suppl 2), 14–19.
   PubMedGoogle Scholar
• Hong, Y., et al., 2015. Growth, digestive and absorptive capacity and antioxidant status in intestine and hepatopancreas of sub-adult grass carp Ctenopharyngodon idella fed graded levels of dietary threonine. Journal of Animal Science and Biotechnology, 6 (1), 34.
   PubMedGoogle Scholar
• Houten, S.M., Watanabe, M., and Auwerx, J., 2006. Endocrine functions of bile acids. The EMBO Journal, 25 (7), 1419–1425.
   PubMed Web of Science ®Google Scholar
• Howe, K., et al., 2013. The zebrafish reference genome sequence and its relationship to the human genome. Nature, 496 (7446), 498–503.
   PubMed Web of Science ®Google Scholar
• Ikeda, Y., Morita, S.Y., and Terada, T., 2017. Cholesterol attenuates cytoprotective effects of phosphatidylcholine against bile salts. Scientific Reports, 7 (1), 306.
   PubMedGoogle Scholar
• Jarocki, P., and Targoński, Z., 2013. Genetic diversity of bile salt hydrolases among human intestinal bifidobacteria. Current Microbiology, 67 (3), 286–292.
   PubMed Web of Science ®Google Scholar
• Johnson, C.D., 2005. UK guidelines for the management of acute pancreatitis. Gut, 54 (SUPPL. 3), 1–10.
   PubMed Web of Science ®Google Scholar
• Johnson, R.W., 2002. The concept of sickness behavior: a brief chronological account of four key discoveries. Veterinary Immunology and Immunopathology, 87 (3–4), 443–450.
   PubMed Web of Science ®Google Scholar
• Kamada, N., et al., 2013. Role of the gut microbiota in immunity and inflammatory disease. Nature Reviews. Immunology, 13 (5), 321–335.
   PubMed Web of Science ®Google Scholar
• Kimmel, C.B., et al., 1995. Stages of embryonic development of the zebrafish. Developmental Dynamics, 203 (3), 253–310.
   PubMed Web of Science ®Google Scholar
• Kirsten, K., et al., 2018. First description of behavior and immune system relationship in fish. Scientific Reports, 8 (1), 846.
   PubMedGoogle Scholar
• Kominsky, D.J., Campbell, E.L., and Colgan, S.P., 2010. Metabolic shifts in immunity and inflammation. Journal of Immunology, 184 (8), 4062–4068.
   PubMed Web of Science ®Google Scholar
• Kominsky, D.J., et al., 2011. An endogenously anti-inflammatory role for methylation in mucosal inflammation identified through metabolite profiling. Journal of Immunology, 186 (11), 6505–6514.
   PubMed Web of Science ®Google Scholar
• Kovács, R., et al., 2016. Acute and sub-chronic toxicity of four cytostatic drugs in zebrafish. Environmental Science and Pollution Research International, 23 (15), 14718–14729.
   PubMed Web of Science ®Google Scholar
• Lewis, J.S., et al., 1999. Macrophage responses to hypoxia: relevance to disease mechanisms. Journal of Leukocyte Biology, 66 (6), 889–900.
   PubMed Web of Science ®Google Scholar
• Li, J., et al., 2014. 1HNMR-based metabolomic profile of rats with experimental acute pancreatitis. BMC Gastroenterology, 14 (1), 115.
   PubMedGoogle Scholar
• Liu, X., et al., 2018. Acetate production from glucose and coupling to mitochondrial metabolism in mammals article acetate production from glucose and coupling to mitochondrial metabolism in mammals. Cell, 175 (2), 502–513.e13.
   PubMed Web of Science ®Google Scholar
• Lou, G., et al., 2014. GPBAR1/TGR5 mediates bile acid-induced cytokine expression in murine Kupffer cells. PLoS One, 9 (4), e93567.
   PubMed Web of Science ®Google Scholar
• Masuda, N., 1981. Deconjugation of bile salts by bacteroides and clostridium. Microbiology and Immunology, 25 (1), 1–11.
   PubMed Web of Science ®Google Scholar
• Miyazaki, K., Nakayama, F., and Koga, A., 1984. Effect of chenodeoxycholic and ursodeoxycholic acids on isolated adult human hepatocytes. Digestive Diseases and Sciences, 29 (12), 1123–1130.
   PubMed Web of Science ®Google Scholar
• Muller, N., J., and Schwarz, M., 2010. The role of immune system in schizophrenia. Current Immunology Reviews, 6 (3), 213–220.
   PubMedGoogle Scholar
• Muoio, D.M., and Newgard, C.B., 2006. Obesity-related derangements in metabolic regulation. Annual Review of Biochemistry, 75, 367–401.
   PubMed Web of Science ®Google Scholar
• Oh, H.K., et al., 2008. Molecular cloning and characterization of a bile salt hydrolase from Lactobacillus acidophilus PF01. Journal of Microbiology and Biotechnology, 18 (3), 449–456.
   PubMed Web of Science ®Google Scholar
• Perez, M.J., and Britz, O., 2009. Bile-acid-induced cell injury and protection. World Journal of Gastroenterology, 15 (14), 1677–1689.
   PubMed Web of Science ®Google Scholar
• Režen, T., et al., 2022. The role of bile acids in carcinogenesis. Cellular and Molecular Life Sciences, 79 (5), 243.
   PubMed Web of Science ®Google Scholar
• Ridlon, J.M., Kang, D.J., and Hylemon, P.B., 2006. Bile salt biotransformations by human intestinal bacteria. Journal of Lipid Research, 47 (2), 241–259.
   PubMed Web of Science ®Google Scholar
• Ridlon, J.M., et al., 2016. Consequences of bile salt biotransformations by intestinal bacteria. Gut Microbes, 7 (1), 22–39.
   PubMed Web of Science ®Google Scholar
• Saadi, S., Wrenshall, L.E., and Platt, J.L., 2002. Regional manifestations and control of the immune system. FASEB Journal, 16 (8), 849–856.
   PubMed Web of Science ®Google Scholar
• Sakai, A., et al., 2012. Metabolomic analysis to discover candidate therapeutic agents against acute pancreatitis. Archives of Biochemistry and Biophysics, 522 (2), 107–120.
   PubMed Web of Science ®Google Scholar
• SchÖLmerich, J., et al., 1984. Influence of hydroxylation and conjugation of bile salts on their membrane-damaging properties-studies on isolated hepatocytes and lipid membrane vesicles. Hepatology, 4 (4), 661–666.
   PubMed Web of Science ®Google Scholar
• Schubert, R., et al., 1986. Structural changes in membranes of large unilamellar vesicles after binding of sodium cholate. Biochemistry, 25 (18), 5263–5269. https://doi.org/10.1021/bi00366a042
   PubMed Web of Science ®Google Scholar
• Shi, Q., et al., 2015. Hydrogen-rich saline attenuates acute renal injury in sodium taurocholate-induced severe acute pancreatitis by inhibiting ROS and NF- B pathway. Mediators of Inflammation, 2015, 685043.
   PubMed Web of Science ®Google Scholar
• Sokol, R.J., et al., 2001. Role of oxidant stress in the permeability transition induced in rat hepatic mitochondria by hydrophobic bile acids. Pediatric Research, 49 (4), 519–531.
   PubMed Web of Science ®Google Scholar
• Sriram, G., et al., 2008. Global metabolic effects of glycerol kinase overexpression in rat hepatoma cells. Molecular Genetics and Metabolism, 93 (2), 145–159.
   PubMed Web of Science ®Google Scholar
• Suarez, R.K., and Mommsen, T.P., 1987. Gluconeogenesis in teleost fishes. Canadian Journal of Zoology, 65 (8), 1869–1882.
   Google Scholar
• Sulaiman, F., et al., 2020. Metabolite profiles of red and yellow watermelon (Citrullus lanatus) cultivars using a 1H-NMR metabolomics approach. Molecules, 25 (14), 1–13.
   Web of Science ®Google Scholar
• Swinnen, J.V., Brusselmans, K., and Verhoeven, G., 2006. Increased lipogenesis in cancer cells: new players, novel targets. Current Opinion in Clinical Nutrition and Metabolic Care, 9 (4), 358–365.
   PubMed Web of Science ®Google Scholar
• Tang, Q., et al., 2021. Physiological functions of threonine in animals: beyond nutrition metabolism. Nutrients, 13 (8), 2592.
   PubMed Web of Science ®Google Scholar
• Tian, N., et al., 2013. NMR-based metabonomic study of Chinese medicine Gegen Qinlian Decoction as an effective treatment for type 2 diabetes in rats. Metabolomics, 9 (6), 1228–1242.
   Web of Science ®Google Scholar
• Van Bossuyt, H., et al., 1990. The role of bile acids in the development of endotoxemia during obstructive jaundice in the rat. Journal of Hepatology, 10 (3), 274–279. https://doi.org/10.1016/0168-8278(90)90132-B
   PubMed Web of Science ®Google Scholar
• Vessey, D.A., 1978. The biochemical basis for the conjugation of bile acids with either glycine or taurine. The Biochemical Journal, 174 (2), 621–626.
   PubMed Web of Science ®Google Scholar
• Wang, W.H., 2012. The elastic properties, elastic models and elastic perspectives of metallic glasses. Progress in Materials Science, 57 (3), 487–656.
   Web of Science ®Google Scholar
• Wang, W., et al., 2013. Glycine metabolism in animals and humans: Implications for nutrition and health. Amino Acids, 45 (3), 463–477.
   PubMed Web of Science ®Google Scholar
• Wang, X., et al., 2007. A deficiency or excess of dietary threonine reduces protein synthesis in jejunum and skeletal muscle of young pigs. The Journal of Nutrition, 137 (6), 1442–1446.
   PubMed Web of Science ®Google Scholar
• Wang, Y., et al., 2017. 1H NMR-based metabolomics analysis of adult zebrafish (Danio rerio) after exposure to diniconazole as well as its bioaccumulation behavior. Chemosphere, 168, 1571–1577.
   PubMed Web of Science ®Google Scholar
• Watanabe, M., et al., 2006. Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature, 439 (7075), 484–489.
   PubMed Web of Science ®Google Scholar
• Wijaya, A., et al., 2004. Cloning of the bile salt hydrolase (bsh) gene from Enterococcus faecium FAIR-E 345 and chromosomal location of bsh genes in food Enterococci. Journal of Food Protection, 67 (12), 2772–2778.
   PubMed Web of Science ®Google Scholar
• Worley, B., and Powers, R., 2013. Multivariate analysis in metabolomics. Current Metabolomics, 1 (1), 92–107.
   PubMedGoogle Scholar
• Xue, L.L., Chen, H.H., and Jiang, J.G., 2017. Implications of glycerol metabolism for lipid production. Progress in Lipid Research, 68, 12–25.
   PubMed Web of Science ®Google Scholar
• Yang, S., et al., 2021. Daphnetin ameliorates acute lung injury in mice with severe acute pancreatitis by inhibiting the JAK2–STAT3 pathway. Scientific Reports, 11 (1), 11491.
   PubMed Web of Science ®Google Scholar
• Zakaria, F., et al., 2021. Perturbations in amino acid metabolism in reserpine-treated zebrafish brain detected by 1H nuclear magnetic resonance-based metabolomics. Zebrafish, 18 (1), 42–54.
   PubMed Web of Science ®Google Scholar