Broadband microwave spiral applicator (105–125 MHz) for in vitro examinations of hyperthermia-induced tumor cell death forms – first analyses with human breast cancer cells

References

• Mattiuzzi C, Lippi G. Current cancer epidemiology. J Epidemiol Glob Health. 2019;9(4):217–222. doi:10.2991/jegh.k.191008.001.
   PubMed Web of Science ®Google Scholar
• Ferlay J, Shin H-R, Bray F, et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010;127(12):2893–2917. doi:10.1002/ijc.25516.
   PubMed Web of Science ®Google Scholar
• Buonomo OC, Caredda E, Portarena I, et al. New insights into the metastatic behavior after breast cancer surgery, according to well-established clinicopathological variables and molecular subtypes. PLoS One. 2017;12(9):e0184680. doi:10.1371/journal.pone.0184680.
   PubMed Web of Science ®Google Scholar
• Onkar SS, Carleton NM, Lucas PC, et al. The great immune escape: understanding the divergent immune response in breast cancer subtypes. Cancer Discov. 2023;13(1):23–40. doi:10.1158/2159-8290.CD-22-0475.
   PubMed Web of Science ®Google Scholar
• Schlam I, Tarantino P, Morganti S, et al. Emerging targeted therapies for early breast cancer. Drugs. 2022;82(14):1437–1451. doi:10.1007/s40265-022-01781-5.
   PubMed Web of Science ®Google Scholar
• Falk MH, Issels RD. Hyperthermia in oncology. Int J Hyperthermia. 2001;17(1):1–18. doi:10.1080/02656730150201552.
   PubMed Web of Science ®Google Scholar
• Peeken JC, Vaupel P, Combs SE. Integrating hyperthermia into modern radiation oncology: what evidence is necessary? Front Oncol. 2017;7:132. doi:10.3389/fonc.2017.00132.
   PubMed Web of Science ®Google Scholar
• Hader M, Frey B, Fietkau R, et al. Immune biological rationales for the design of combined radio- and immunotherapies. Cancer Immunol Immunother. 2020;69(2):293–306. doi:10.1007/s00262-019-02460-3.
   PubMed Web of Science ®Google Scholar
• Klimanov MY, Syvak LA, Orel VE, et al. Efficacy of combined regional inductive moderate hyperthermia and chemotherapy in patients with multiple liver metastases from breast cancer. Technol Cancer Res Treat. 2018;17:153303381880600. doi:10.1177/1533033818806003.
   Web of Science ®Google Scholar
• Wittlinger M, Rödel CM, Weiss C, et al. Quadrimodal treatment of high-risk T1 and T2 bladder cancer: transurethral tumor resection followed by concurrent radiochemotherapy and regional deep hyperthermia. Radiother Oncol. 2009;93(2):358–363. doi:10.1016/j.radonc.2009.09.018.
   PubMed Web of Science ®Google Scholar
• Huilgol NG, Gupta S, Sridhar C. Hyperthermia with radiation in the treatment of locally advanced head and neck cancer: a report of randomized trial. J Cancer Res Ther. 2010;6(4):492–496. doi:10.4103/0973-1482.77101.
   PubMed Web of Science ®Google Scholar
• Issels RD, Lindner LH, Wessalowski R, et al. Neo-adjuvant chemotherapy alone or with regional hyperthermia for localised high-risk soft-tissue sarcoma: a randomised phase 3 multicentre study. Lancet Oncol. 2017;18(11):e630–570. doi:10.1016/S1470-2045(10)70071-1.
   PubMed Web of Science ®Google Scholar
• Toraya-Brown S, Fiering S. Local tumour hyperthermia as immunotherapy for metastatic cancer. Int J Hyperthermia. 2014;30(8):531–539. doi:10.3109/02656736.2014.968640.
   PubMed Web of Science ®Google Scholar
• Hader M, Savcigil DP, Rosin A, et al. Differences of the immune phenotype of breast cancer cells after ex vivo hyperthermia by Warm-Water or microwave radiation in a Closed-Loop system alone or in combination with radiotherapy. Cancers (Basel). 2020;12(5):1082. doi:10.3390/cancers12051082.
   PubMed Web of Science ®Google Scholar
• Hader M, Streit S, Rosin A, et al. In vitro examinations of cell death induction and the immune phenotype of cancer cells following Radiative-Based hyperthermia with 915 MHz in combination with radiotherapy. Cells. 2021;10(6):1436. doi:10.3390/cells10061436.
   PubMed Web of Science ®Google Scholar
• Oei AL, Kok HP, Oei SB, et al. Molecular and biological rationale of hyperthermia as radio- and chemosensitizer. Adv Drug Deliv Rev. 2020;163–164:84–97. doi:10.1016/j.addr.2020.01.003.
   PubMed Web of Science ®Google Scholar
• Altintas G, Akduman I, Janjic A, et al. A novel approach on microwave hyperthermia. Diagnostics. 2021;11(3):493. doi:10.3390/diagnostics11030493.
   Web of Science ®Google Scholar
• Harrison WH, Storm FK, Elliott RS, et al. A comparison of deep-heating electrode concepts for hyperthermia. J Microw Power Electromagn Energy. 1985;20(1):1–8. doi:10.1080/16070658.1985.11720273.
   PubMed Web of Science ®Google Scholar
• Sengedorj A, Hader M, Heger L, et al. The effect of hyperthermia and radiotherapy sequence on cancer cell death and the immune phenotype of breast cancer cells. Cancers (Basel). 2022;14(9):2050. doi:10.3390/cancers14092050.
   PubMed Web of Science ®Google Scholar
• Bakker A, et al. Temperature and thermal dose during radiotherapy and hyperthermia for recurrent breast cancer are related to clinical outcome and thermal toxicity: a systematic review. Int J Hyperthermia. 2019;36(1):1024–1039.
   PubMed Web of Science ®Google Scholar
• Crezee H, Kok HP, Oei AL, et al. The impact of the time interval between radiation and hyperthermia on clinical outcome in patients with locally advanced cervical cancer. Front Oncol. 2019;9:412. doi:10.3389/fonc.2019.00412.
   PubMed Web of Science ®Google Scholar
• Dobšíček Trefná H, et al. Quality assurance guidelines for interstitial hyperthermia. Int J Hyperthermia. 2019;36(1):277–294.
   PubMed Web of Science ®Google Scholar
• Lagendijk JJ, Van Rhoon GC, Hornsleth SN, et al. ESHO quality assurance guidelines for regional hyperthermia. Int J Hyperthermia. 1998;14(2):125–133. doi:10.3109/02656739809018219.
   PubMed Web of Science ®Google Scholar
• Elming PB, Sørensen BS, Oei AL, et al. Hyperthermia: the optimal treatment to overcome radiation resistant hypoxia. Cancers (Basel). 2019;11(1):60. doi:10.3390/cancers11010060.
   PubMed Web of Science ®Google Scholar
• Dobšíček Trefná H, Crezee J, Schmidt M, et al. Quality assurance guidelines for superficial hyperthermia clinical trials: II. Technical requirements for heating devices. Strahlenther Onkol. 2017;193(5):351–366. doi:10.1007/s00066-017-1106-0.
   PubMed Web of Science ®Google Scholar
• Müller J, Hartmann J, Bert C. Infrared camera based thermometry for quality assurance of superficial hyperthermia applicators. Phys Med Biol. 2016;61(7):2646–2664. doi:10.1088/0031-9155/61/7/2646.
   PubMed Web of Science ®Google Scholar
• Stoll E, Hader M, Rückert M, et al. Detailed in vitro analyses of the impact of multimodal cancer therapy with hyperthermia and radiotherapy on the immune phenotype of human glioblastoma cells. Int J Hyperthermia. 2022;39(1):796–805. doi:10.1080/02656736.2022.2080873.
   PubMed Web of Science ®Google Scholar
• Gaipl US, Kuenkele S, Voll RE, et al. Complement binding is an early feature of necrotic and a rather late event during apoptotic cell death. Cell Death Differ. 2001;8(4):327–334. doi:10.1038/sj.cdd.4400826.
   PubMed Web of Science ®Google Scholar
• Henry CM, Hollville E, Martin SJ. Measuring apoptosis by microscopy and flow cytometry. Methods. 2013;61(2):90–97. doi:10.1016/j.ymeth.2013.01.008.
   PubMed Web of Science ®Google Scholar
• Wang S, He M, Li L, et al. Cell-in-Cell death is not restricted by caspase-3 deficiency in MCF-7 cells. J Breast Cancer. 2016;19(3):231–241. doi:10.4048/jbc.2016.19.3.231.
   PubMed Web of Science ®Google Scholar
• Kok HP, Crezee J. A comparison of the heating characteristics of capacitive and radiative superficial hyperthermia. Int J Hyperthermia. 2017;33(4):378–386. doi:10.1080/02656736.2016.1268726.
   PubMed Web of Science ®Google Scholar
• Yang Y, Yang C-L, Zhao Z-J, et al. Microwave hyperthermia enhances the sensitivity of lung cancer cells to gemcitabine through reactive oxygen species‑induced autophagic death. Oncol Rep. 2019;41(5):3100–3110. doi:10.3892/or.2019.7085.
   PubMed Web of Science ®Google Scholar
• von Euw EM, Barrio MM, Furman D, et al. Monocyte-derived dendritic cells loaded with a mixture of apoptotic/necrotic melanoma cells efficiently cross-present gp100 and MART-1 antigens to specific CD8(+) T lymphocytes. J Transl Med. 2007;5(1):19. doi:10.1186/1479-5876-5-19.
   PubMedGoogle Scholar
• Schulze C, Munoz LE, Franz S, et al. Clearance deficiency–a potential link between infections and autoimmunity. Autoimmun Rev. 2008;8(1):5–8. doi:10.1016/j.autrev.2008.07.049.
   PubMed Web of Science ®Google Scholar
• Tait SW, Green DR. Caspase-independent cell death: leaving the set without the final cut. Oncogene. 2008;27(50):6452–6461. doi:10.1038/onc.2008.311.
   PubMed Web of Science ®Google Scholar
• Werthmöller N, Frey B, Rückert M, et al. Combination of ionising radiation with hyperthermia increases the immunogenic potential of B16-F10 melanoma cells in vitro and in vivo. Int J Hyperthermia. 2016;32(1):23–30. doi:10.3109/02656736.2015.1106011.
   PubMed Web of Science ®Google Scholar
• Emens LA. Breast cancer immunotherapy: facts and hopes. Clin Cancer Res. 2018;24(3):511–520. doi:10.1158/1078-0432.CCR-16-3001.
   PubMed Web of Science ®Google Scholar
• Piroth MD, Krig D, Feyer P, et al. Oligometastasis in breast cancer—current status and treatment options from a radiation oncology perspective. Strahlenther Onkol. 2022;198(7):601–611. doi:10.1007/s00066-022-01938-x.
   PubMed Web of Science ®Google Scholar