MAO inhibiting phytochemicals from the roots of Glycyrrhiza glabra L.

References

• Akamatsu, H., Komura, J., Asada, Y., & Niwa, Y. (1991). Mechanism of anti-inflammatory action of glycyrrhizin: Effect on neutrophil functions including reactive oxygen species generation. Planta Medica, 57(2), 119–121. https://doi.org/10.1055/s-2006-960045
   PubMed Web of Science ®Google Scholar
• Alnajjar, R., Mohamed, N., & Kawafi, N. (2021). Bicyclo [1.1. 1] Pentane as phenyl substituent in atorvastatin drug to improve physicochemical properties: Drug-likeness, DFT, pharmacokinetics, docking, and molecular dynamic simulation. Journal of Molecular Structure, 1230, 129628. https://doi.org/10.1016/j.molstruc.2020.129628
   Web of Science ®Google Scholar
• Ambavade, S. D., Kasture, V. S., & Kasture, S. B. (2001). Anxiolytic activity of Glycyrrhiza glabra Linn. Journal of Natural Remedies, 1, 130–134.
   Google Scholar
• Arazo, M., Bello, A., Rastrelli, L., Montelier, M., Delgado, L., & Panfet, C. (2011). Antioxidant properties of pulp and peel of yellow mangosteenfruits. Emirates Journal of Food and Agriculture, 23(6), 517–524.
   Google Scholar
• Asl, M. N., & Hosseinzadeh, H. (2008). Review of pharmacological effects of Glycyrrhiza sp. and its bioactive compounds. Phytotherapy Research: PTR, 22(6), 709–724. https://doi.org/10.1002/ptr.2362
   PubMed Web of Science ®Google Scholar
• Bar Am, O., Amit, T., & Youdim, M. B. H. (2004). Contrasting neuroprotective and neurotoxic actions of respective metabolites of anti-Parkinson drugs rasagiline and selegiline. Neuroscience Letters, 355(3), 169–172. https://doi.org/10.1016/j.neulet.2003.10.067
   PubMed Web of Science ®Google Scholar
• Berman, S. B., & Hastings, T. G. (1999). Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: Implications for Parkinson’s disease. Journal of Neurochemistry, 73(3), 1127–1137. https://doi.org/10.1046/j.1471-4159.1999.0731127.x
   PubMed Web of Science ®Google Scholar
• Bhattacharjee, M., Manoharan, S., Deshetty, U. M., & Perumal, E. (2023). Acute hypobaric hypoxia exposure causes neurobehavioral impairments in rats: Role of brain catecholamines and tetrahydrobiopterin alterations. Neurochemical Research, 48(2), 471–486. https://doi.org/10.1007/s11064-022-03767-x
   PubMed Web of Science ®Google Scholar
• Bhattacharjee, M., & Perumal, E. (2019). Potential plant-derived catecholaminergic activity enhancers for neuropharmacological approaches: A review. Phytomedicine: International Journal of Phytotherapy and Phytopharmacology, 55, 148–164. https://doi.org/10.1016/j.phymed.2018.07.010
   PubMed Web of Science ®Google Scholar
• Blier, P., & De Montigny, C. (1994). Current advances and trends in the treatment of depression. Trends in Pharmacological Sciences, 15(7), 220–226. https://doi.org/10.1016/0165-6147(94)90315-8
   PubMed Web of Science ®Google Scholar
• Bordoli, L., & Schwede, T. (2012). Automated protein structure modeling with SWISS-MODEL Workspace and the Protein Model Portal. Homology Modeling: Methods and Protocols, 857, 107–136.
   Google Scholar
• Buigues, J., & Vallejo, J. (1987). Therapeutic response to phenelzine in patients with panic disorder and agoraphobia with panic attacks. J Clin Psychiatry, 48(2), 55–59.
   PubMed Web of Science ®Google Scholar
• Bürgers, R., Gerlach, T., Hahnel, S., Schwarz, F., Handel, G., & Gosau, M. (2010). In vivo and in vitro biofilm formation on two different titanium implant surfaces. Clinical Oral Implants Research, 21(2), 156–164. https://doi.org/10.1111/j.1600-0501.2009.01815.x
   PubMed Web of Science ®Google Scholar
• Chan, F. K. M., Moriwaki, K., & De Rosa, M. J. (2013). Detection of necrosis by release of lactate dehydrogenase activity. Immune Homeostasis: Methods and Protocols, 979, 65–70.
   Google Scholar
• Chin, Y.-W., Jung, H.-A., Liu, Y., Su, B.-N., Castoro, J. A., Keller, W. J., Pereira, M. A., & Kinghorn, A. D. (2007). Anti-oxidant constituents of the roots and stolons of licorice (Glycyrrhiza glabra). Journal of Agricultural and Food Chemistry, 55(12), 4691–4697. https://doi.org/10.1021/jf0703553
   PubMed Web of Science ®Google Scholar
• Chopra, P. K. P. G., Saraf, B. D., Inam, F. A. R. H. I. N., & Deo, S. S. (2013). Antimicrobial and antioxidant activities of methanol extract roots of Glycyrrhiza glabra and HPLC analysis. International Journal of Pharmacy and Pharmaceutical Sciences, 5(2), 157–160.
   Google Scholar
• Cornelius, J. R., Soloff, P. H., Perel, J. M., & Ulrich, R. F. (1993). Continuation pharmacotherapy of borderline personality disorder with haloperidol and phenelzine. The American Journal of Psychiatry, 150(12), 1843–1848.
   PubMed Web of Science ®Google Scholar
• Dahal, R. A., Pramod, A. B., Sharma, B., Krout, D., Foster, J. D., Cha, J. H., Cao, J., Newman, A. H., Lever, J. R., Vaughan, R. A., & Henry, L. K. (2014). Computational and biochemical docking of the irreversible cocaine analog RTI 82 directly demonstrates ligand positioning in the dopamine transporter central substrate-binding site. The Journal of Biological Chemistry, 289(43), 29712–29727. https://doi.org/10.1074/jbc.M114.571521
   PubMed Web of Science ®Google Scholar
• Daina, A., Michielin, O., & Zoete, V. (2017). SwissADME: A free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules. Scientific Reports, 7(1), 42717. https://doi.org/10.1038/srep42717
   PubMed Web of Science ®Google Scholar
• Davidson, J., Kudler, H., & Smith, R. (1987). Personality in chronic post-traumatic stress disorder: A study of the eysenck inventory. Journal of Anxiety Disorders, 1(4), 295–300. https://doi.org/10.1016/0887-6185(87)90009-0
   Google Scholar
• De Colibus, L., Li, M., Binda, C., Lustig, A., Edmondson, D. E., & Mattevi, A. (2005). Three-dimensional structure of human monoamine oxidase A (MAO A): Relation to the structures of rat MAO A and human MAO B. Proceedings of the National Academy of Sciences of the United States of America, 102(36), 12684–12689. https://doi.org/10.1073/pnas.0505975102
   PubMed Web of Science ®Google Scholar
• Deshetty, U. M., Tamatam, A., Bhattacharjee, M., Perumal, E., Natarajan, G., & Khanum, F. (2020). Ameliorative effect of hesperidin against motion sickness by modulating histamine and histamine H1 receptor expression. Neurochemical Research, 45(2), 371–384. https://doi.org/10.1007/s11064-019-02923-0
   PubMed Web of Science ®Google Scholar
• Dhingra, D., Parle, M., & Kulkarni, S. K. (2004). Memory enhancing activity of Glycyrrhiza glabra in mice. Journal of Ethnopharmacology, 91(2–3), 361–365. https://doi.org/10.1016/j.jep.2004.01.016
   PubMed Web of Science ®Google Scholar
• Dhingra, D., & Sharma, A. (2005). Evaluation of antidepressant-like activity of glycyrrhizin in mice. Indian Journal of Pharmacology, 37(6), 390. https://doi.org/10.4103/0253-7613.19077
   Google Scholar
• Dhingra, D., & Sharma, A. (2006). Antidepressant-like activity of Glycyrrhiza glabra L. in mouse models of immobility tests. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 30(3), 449–454. https://doi.org/10.1016/j.pnpbp.2005.11.019
   PubMed Web of Science ®Google Scholar
• Ekins, S., Liebler, J., Neves, B. J., Lewis, W. G., Coffee, M., Bienstock, R., … Andrade, C. H. (2016). Illustrating and homology modeling the proteins of the Zika virus [version 2; referees: 2 approved].
   Google Scholar
• Field, M., Sheerin, H. E., Henderson, A., & Smith, P. L. (1975). Catecholamine effects on cyclic AMP levels and ion secretion in rabbit ileal mucosa. The American Journal of Physiology, 229(1), 86–92. https://doi.org/10.1152/ajplegacy.1975.229.1.86
   PubMedGoogle Scholar
• Finberg, J. P., & Rabey, J. M. (2016). Inhibitors of MAO-A and MAO-B in psychiatry and neurology. Frontiers in Pharmacology, 7, 340. https://doi.org/10.3389/fphar.2016.00340
   PubMed Web of Science ®Google Scholar
• Fukai, T., Nomura, T., Nomura, T., & Fukai, T. (1998). Phenolic constituents of licorice (Glycyrrhiza species). Fortschritte Der Chemie Organischer Naturstoffe/Progress in the Chemistry of Organic Natural Products, 73, 1–140.
   PubMedGoogle Scholar
• Govindasamy, H., Magudeeswaran, S., Kandasamy, S., & Poomani, K. (2021). Binding mechanism of naringenin with monoamine oxidase–B enzyme: QM/MM and molecular dynamics perspective. Heliyon, 7(4), e06684. https://doi.org/10.1016/j.heliyon.2021.e06684
   PubMed Web of Science ®Google Scholar
• Hamel, E. (2007). Serotonin and migraine: Biology and clinical implications. Cephalalgia: An International Journal of Headache, 27(11), 1293–1300. https://doi.org/10.1111/j.1468-2982.2007.01476.x
   PubMed Web of Science ®Google Scholar
• Haraguchi, H., Tanaka, Y., Kabbash, A., Fujioka, T., Ishizu, T., & Yagi, A. (2004). Monoamine oxidase inhibitors from Gentiana lutea. Phytochemistry, 65(15), 2255–2260. https://doi.org/10.1016/j.phytochem.2004.06.025
   PubMed Web of Science ®Google Scholar
• Harder, E., Damm, W., Maple, J., Wu, C., Reboul, M., Xiang, J. Y., Wang, L., Lupyan, D., Dahlgren, M. K., Knight, J. L., Kaus, J. W., Cerutti, D. S., Krilov, G., Jorgensen, W. L., Abel, R., & Friesner, R. A. (2016). OPLS3: A force field providing broad coverage of drug-like small molecules and proteins. Journal of Chemical Theory and Computation, 12(1), 281–296. https://doi.org/10.1021/acs.jctc.5b00864
   PubMed Web of Science ®Google Scholar
• Henriot, S., Kuhn, C., Kettler, R., & Da Prada, M. (1994). Lazabemide (Ro 19-6327), a reversible and highly sensitive MAO-B inhibitor: Preclinical and clinical findings. In Amine Oxidases: Function and Dysfunction: Proceedings of the 5 th International Amine Oxidase Workshop, Galway, Ireland, August 22–25, 1992 (pp. 321–325). Springer.
   Google Scholar
• Honda, I., Araki, K., Honda, S., Soeda, F., Shin, M.-C., Misumi, S., Yamamura, K.-I., & Takahama, K. (2018). Deletion of GIRK2 subunit containing GIRK channels of neurons expressing dopamine transporter decrease immobility time on forced swimming in mice. Neuroscience Letters, 665, 140–146. https://doi.org/10.1016/j.neulet.2017.11.028
   PubMed Web of Science ®Google Scholar
• Ismail, N. A., & Jusoh, S. A. (2017). Molecular docking and molecular dynamics simulation studies to predict flavonoid binding on the surface of DENV2 E protein. Interdisciplinary Sciences, Computational Life Sciences, 9(4), 499–511. https://doi.org/10.1007/s12539-016-0157-8
   PubMed Web of Science ®Google Scholar
• Jeong, G. S., Kang, M. G., Lee, J. Y., Lee, S. R., Park, D., Cho, M., & Kim, H. (2020). Inhibition of butyrylcholinesterase and human monoamine oxidase-B by the coumarin glycyrol and liquiritigenin isolated from Glycyrrhiza uralensis. Molecules, 25(17), 3896. https://doi.org/10.3390/molecules25173896
   PubMed Web of Science ®Google Scholar
• Jorgensen, W. L., Chandrasekhar, J., Madura, J. D., Impey, R. W., & Klein, M. L. (1983). Comparison of simple potential functions for simulating liquid water. The Journal of Chemical Physics, 79(2), 926–935. https://doi.org/10.1063/1.445869
   Web of Science ®Google Scholar
• Kamei, J., Nakamura, R., Ichiki, H., & Kubo, M. (2003). Antitussive principles of Glycyrrhizae radix, a main component of the Kampo preparations Bakumondo-to (Mai-Men-Dong-Tang). European Journal of Pharmacology, 469(1-3), 159–163. https://doi.org/10.1016/s0014-2999(03)01728-x
   PubMed Web of Science ®Google Scholar
• Kawakami, Z., Ikarashi, Y., & Kase, Y. (2010). Glycyrrhizin and its metabolite 18β-glycyrrhetinic acid in glycyrrhiza, a constituent herb of yokukansan, ameliorate thiamine deficiency-induced dysfunction of glutamate transport in cultured rat cortical astrocytes. European Journal of Pharmacology, 626(2-3), 154–158. https://doi.org/10.1016/j.ejphar.2009.09.046
   PubMed Web of Science ®Google Scholar
• Kawaura, K., Ogata, Y., Honda, S., Soeda, F., Shirasaki, T., & Takahama, K. (2016). Tipepidine, a non-narcotic antitussive, exerts an antidepressant-like effect in the forced swimming test in adrenocorticotropic hormone-treated rats. Behavioural Brain Research, 302, 269–278. https://doi.org/10.1016/j.bbr.2015.12.008
   PubMed Web of Science ®Google Scholar
• Knable, M. B., & Weinberger, D. R. (1997). Dopamine, the prefrontal cortex and schizophrenia. Journal of Psychopharmacology (Oxford, England), 11(2), 123–131. https://doi.org/10.1177/026988119701100205
   PubMed Web of Science ®Google Scholar
• Kuang, Y., Li, B., Fan, J., Qiao, X., & Ye, M. (2018). Antitussive and expectorant activities of licorice and its major compounds. Bioorganic & Medicinal Chemistry, 26(1), 278–284. https://doi.org/10.1016/j.bmc.2017.11.046
   PubMed Web of Science ®Google Scholar
• Laban, T. S., & Saadabadi, A. (2022). Monoamine oxidase inhibitors (MAOI). In StatPearls [Internet]. StatPearls Publishing.
   Google Scholar
• Lawal, M., Olotu, F. A., & Soliman, M. E. (2018). Across the blood-brain barrier: Neurotherapeutic screening and characterization of naringenin as a novel CRMP-2 inhibitor in the treatment of Alzheimer’s disease using bioinformatics and computational tools. Computers in Biology and Medicine, 98, 168–177. https://doi.org/10.1016/j.compbiomed.2018.05.012
   PubMed Web of Science ®Google Scholar
• Lee, H. J., Yoon, M. Y., Kim, J. Y., Kim, Y. S., Park, H. R., & Park, E. J. (2008). Antioxidant activity of Glycyrrhiza uralensis fisch extracts on hydrogen peroxide-induced DNA damage in human leucocytes and cell death in PC12 cells. Food Science and Biotechnology, 17(2), 343–348.
   Web of Science ®Google Scholar
• Lippman, S. B., & Nash, K. (1991). Monoamine oxidase inhibitor update: Potential adverse food and drug interactions. Current Therapeutics, 32(2), 76–82.
   Google Scholar
• Ma, J., Yoshimura, M., Yamashita, E., Nakagawa, A., Ito, A., & Tsukihara, T. (2004). Structure of rat monoamine oxidase A and its specific recognitions for substrates and inhibitors. Journal of Molecular Biology, 338(1), 103–114. https://doi.org/10.1016/j.jmb.2004.02.032
   PubMed Web of Science ®Google Scholar
• Mallikharjuna, P. B., Rajanna, L. N., Seetharam, Y. N., & Sharanabasappa, G. K. (2007). Phytochemical studies of Strychnos potatorum Lf-A medicinal plant. E-Journal of Chemistry, 4(4), 510–518. https://doi.org/10.1155/2007/687859
   Google Scholar
• Manoharan, S., Balakrishnan, A., Hemamalini, V., & Perumal, E. (2022). Screening of potent STAT3-SH2 domain inhibitors from JAK/STAT compound library through molecular dynamics simulation. Molecular Diversity, 1–12. https://doi.org/10.1007/s11030-022-10490-w
   Google Scholar
• Manoharan, S., Vedagiri, H., & Perumal, E. (2023). Potent FOXO3a activators from biologically active compound library for cancer therapeutics: an in silico approach. Applied Biochemistry and Biotechnology, 1–24. https://doi.org/10.1007/s12010-023-04470-5
   Web of Science ®Google Scholar
• Martyna, G. J., Klein, M. L., & Tuckerman, M. (1992). Nosé–Hoover chains: The canonical ensemble via continuous dynamics. The Journal of Chemical Physics, 97(4), 2635–2643. https://doi.org/10.1063/1.463940
   Web of Science ®Google Scholar
• Martyna, G. J., Tobias, D. J., & Klein, M. L. (1994). Constant pressure molecular dynamics algorithms. The Journal of Chemical Physics, 101(5), 4177–4189. https://doi.org/10.1063/1.467468
   Web of Science ®Google Scholar
• Mazzio, E., Deiab, S., Park, K., & Soliman, K. F. A. (2013). High throughput screening to identify natural human monoamine oxidase B inhibitors. Phytotherapy Research: PTR, 27(6), 818–828. https://doi.org/10.1002/ptr.4795
   PubMed Web of Science ®Google Scholar
• Mitscher, L. A., Park, Y. H., Clark, D., & Beal, J. L. (1980). Antimicrobial agents from higher plants. Antimicrobial isoflavanoids and related substances from Glycyrrhiza glabra L. var. typica. Journal of Natural Products, 43(2), 259–269. https://doi.org/10.1021/np50008a004
   PubMed Web of Science ®Google Scholar
• Mohammad Yousuf Harun, B., Rafiqul, I., Saifuddin Murad, B., & Abm Robiul, I. (2015). Standardization, quality control and pharmacological review on Glycyrrhiza glabra L. A potential medicinal herb in Unani and Ayurvedic systems of medicine.
   Google Scholar
• Nagatsu, T., & Sawada, M. (2009). L-dopa therapy for Parkinson’s disease: Past, present, and future. Parkinsonism & Related Disorders, 15, S3–S8. https://doi.org/10.1016/S1353-8020(09)70004-5
   PubMed Web of Science ®Google Scholar
• Neria, E., Fischer, S., & Karplus, M. (1996). Simulation of activation free energies in molecular systems. The Journal of Chemical Physics, 105(5), 1902–1921. https://doi.org/10.1063/1.472061
   Web of Science ®Google Scholar
• Nitalikar, M. M., Munde, K. C., Dhore, B. V., & Shikalgar, S. N. (2010). Studies of antibacterial activities of Glycyrrhiza glabra root extract. Int J Pharm Tech Res, 2(1), 899–901.
   Google Scholar
• Olsen, H. T., Stafford, G. I., Van Staden, J., Christensen, S. B., & Jäger, A. K. (2008). Isolation of the MAO-inhibitor naringenin from Mentha aquatica L. Journal of Ethnopharmacology, 117(3), 500–502. https://doi.org/10.1016/j.jep.2008.02.015
   PubMed Web of Science ®Google Scholar
• Pan, X., Kong, L. D., Zhang, Y., Cheng, C. H., & Tan, R. X. (2000). In vitro inhibition of rat monoamine oxidase by liquiritigenin and isoliquiritigenin isolated from Sinofranchetia chinensis. Acta Pharmacologica Sinica, 21(10), 949–953.
   PubMed Web of Science ®Google Scholar
• Pardeshi, S. K. (2019). Food safety and standards act (FSSA) 2006 (34 OF 2006): Its legal provisions, penalties and offences. International Journal of Engineering, Science and Mathematics, 8(7), 78–91.
   Google Scholar
• Prajapati, S. M., & Patel, B. R. (2013). Phyto pharmacological perspective of Yashtimadhu Glycyrrhiza glabra LINN A review. Int J Pharm Biol Arch, 4(5), 833–841.
   Google Scholar
• Racková, L., Jancinová, V., Petríková, M., Drábiková, K., Nosál, R., Stefek, M., Kostálová, D., Prónayová, N., & Kovácová, M. (2007). Mechanism of anti-inflammatory action of liquorice extract and glycyrrhizin. Natural Product Research, 21(14), 1234–1241. https://doi.org/10.1080/14786410701371280
   PubMed Web of Science ®Google Scholar
• Release, S. (2017a). 3: Desmond molecular dynamics system, DE Shaw research. Maestro-Desmond Interoperability Tools. Schrödinger.
   Google Scholar
• Release, S. (2017b). 4: Desmond molecular dynamics system. DE Shaw Research.
   Google Scholar
• Roy, A., Yang, J., & Zhang, Y. (2012). COFACTOR: An accurate comparative algorithm for structure-based protein function annotation. Nucleic Acids Research, 40(Web Server issue), W471–W477. https://doi.org/10.1093/nar/gks372
   PubMedGoogle Scholar
• Sanchez, I., Gomez-Garibay, F., Taboada, J., & Ruiz, B. H. (2000). Antiviral effect of flavonoids on the dengue virus. Phytotherapy Research, 14(2), 89–92. https://doi.org/10.1002/(SICI)1099-1573(200003)14:2<89::AID-PTR569>3.0.CO;2-C
   PubMed Web of Science ®Google Scholar
• Saxena, S. (2005). Glycyrrhiza glabra: Medicine over the millennium.
   Google Scholar
• Schapira, A. H. (2010). Safinamide in the treatment of Parkinson’s disease. Expert Opinion on Pharmacotherapy, 11(13), 2261–2268. https://doi.org/10.1517/14656566.2010.511612
   PubMed Web of Science ®Google Scholar
• Shekhar, M. S., Venkatachalam, T., Sharma, C. S., Singh, H. P., Kalra, S., & Kumar, N. (2019). Computational investigation of binding mechanism of substituted pyrazinones targeting corticotropin releasing factor-1 receptor deliberated for anti-depressant drug design. Journal of Biomolecular Structure and Dynamics, 37(12), 3226–3244. https://doi.org/10.1080/07391102.2018.1513379
   PubMed Web of Science ®Google Scholar
• Siracusa, L., Saija, A., Cristani, M., Cimino, F., D'Arrigo, M., Trombetta, D., Rao, F., & Ruberto, G. (2011). Phytocomplexes from liquorice (Glycyrrhiza glabra L.) leaves—Chemical characterization and evaluation of their antioxidant, anti-genotoxic and anti-inflammatory activity. Fitoterapia, 82(4), 546–556. https://doi.org/10.1016/j.fitote.2011.01.009
   PubMed Web of Science ®Google Scholar
• Son, S. Y., Ma, J., Kondou, Y., Yoshimura, M., Yamashita, E., & Tsukihara, T. (2008). Structure of human monoamine oxidase A at 2.2-Å resolution: The control of opening the entry for substrates/inhibitors. Proceedings of the National Academy of Sciences of the United States of America, 105(15), 5739–5744. https://doi.org/10.1073/pnas.0710626105
   PubMed Web of Science ®Google Scholar
• Stangherlin, A., Gesellchen, F., Zoccarato, A., Terrin, A., Fields, L. A., Berrera, M., Surdo, N. C., Craig, M. A., Smith, G., Hamilton, G., & Zaccolo, M. (2011). cGMP signals modulate cAMP levels in a compartment-specific manner to regulate catecholamine-dependent signaling in cardiac myocytes. Circulation Research, 108(8), 929–939. https://doi.org/10.1161/CIRCRESAHA.110.230698
   PubMed Web of Science ®Google Scholar
• Stein, D. J., Cameron, A., Amrein, R., & Montgomery, S. A. (2002). Moclobemide is effective and well tolerated in the long-term pharmacotherapy of social anxiety disorder with or without comorbid anxiety disorder. International Clinical Psychopharmacology, 17(4), 161–170. https://doi.org/10.1097/00004850-200207000-00002
   PubMed Web of Science ®Google Scholar
• Stewart, J. W., Quitkin, F. M., & Klein, D. F. (1992). The pharmacotherapy of minor depression. American Journal of Psychotherapy, 46(1), 23–36. https://doi.org/10.1176/appi.psychotherapy.1992.46.1.23
   PubMed Web of Science ®Google Scholar
• Tabuchi, M., Imamura, S., Kawakami, Z., Ikarashi, Y., & Kase, Y. (2012). The blood–brain barrier permeability of 18β-glycyrrhetinic acid, a major metabolite of glycyrrhizin in Glycyrrhiza root, a constituent of the traditional Japanese medicine yokukansan. Cellular and Molecular Neurobiology, 32(7), 1139–1146. https://doi.org/10.1007/s10571-012-9839-x
   PubMed Web of Science ®Google Scholar
• Wei, W., Gao, X., Zhao, L., Zhuang, J., Jiao, Y., & Xu, F. (2020). Liquiritin apioside attenuates laryngeal chemoreflex but not mechanoreflex in rat pups. American Journal of Physiology. Lung Cellular and Molecular Physiology, 318(1), L89–L97. https://doi.org/10.1152/ajplung.00306.2019
   PubMed Web of Science ®Google Scholar
• Xie, Y., Zhao, W., Zhou, T., Fan, G., & Wu, Y. (2010). An efficient strategy based on MAE, HPLC‐DAD‐ESI‐MS/MS and 2D‐prep‐HPLC‐DAD for the rapid extraction, separation, identification and purification of five active coumarin components from radix angelicae dahuricae. Phytochemical Analysis: PCA, 21(5), 473–482. https://doi.org/10.1002/pca.1222
   PubMed Web of Science ®Google Scholar
• Yang, J., & Zhang, Y. (2015). I-TASSER server: New development for protein structure and function predictions. Nucleic Acids Research, 43(W1), W174–W181. https://doi.org/10.1093/nar/gkv342
   PubMed Web of Science ®Google Scholar
• Youdim, M. B., & Bakhle, Y. S. (2006). Monoamine oxidase: Isoforms and inhibitors in Parkinson’s disease and depressive illness. British Journal of Pharmacology, 147(S1), S287–S296. https://doi.org/10.1038/sj.bjp.0706464
   PubMed Web of Science ®Google Scholar
• Youdim, M. B., Edmondson, D., & Tipton, K. F. (2006). The therapeutic potential of monoamine oxidase inhibitors. Nature Reviews. Neuroscience, 7(4), 295–309. https://doi.org/10.1038/nrn1883
   PubMed Web of Science ®Google Scholar
• Zhang, Y. (2009). I‐TASSER: Fully automated protein structure prediction in CASP8. Proteins: Structure, Function, and Bioinformatics, 77(S9), 100–113. https://doi.org/10.1002/prot.22588
   PubMedGoogle Scholar